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NLRP3 licenses NLRP11 for inflammasome activation in human macrophages.
Gangopadhyay A, Devi S, Tenguria S, Carriere J, Nguyen H, Jäger E, Khatri H, Chu LH, Ratsimandresy RA, Dorfleutner A, Stehlik C. Gangopadhyay A, et al. Nat Immunol. 2022 Jun;23(6):892-903. doi: 10.1038/s41590-022-01220-3. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624206 Free PMC article.
POP1 inhibits MSU-induced inflammasome activation and ameliorates gout.
de Almeida L, Devi S, Indramohan M, Huang QQ, Ratsimandresy RA, Pope RM, Dorfleutner A, Stehlik C. de Almeida L, et al. Front Immunol. 2022 Sep 26;13:912069. doi: 10.3389/fimmu.2022.912069. eCollection 2022. Front Immunol. 2022. PMID: 36225929 Free PMC article.