R01 AI150451/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	5
2020	9
2021	4
2023	1
2024	1

1

The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity.

Prasad CB, Oo A, Liu Y, Qiu Z, Zhong Y, Li N, Singh D, Xin X, Cho YJ, Li Z, Zhang X, Yan C, Zheng Q, Wang QE, Guo D, Kim B, Zhang J. Prasad CB, et al. Nat Commun. 2024 May 31;15(1):4667. doi: 10.1038/s41467-024-48076-9. Nat Commun. 2024. PMID: 38821952 Free PMC article.

2

The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer.

Gandhi M, Groß M, Holler JM, Coggins SA, Patil N, Leupold JH, Munschauer M, Schenone M, Hartigan CR, Allgayer H, Kim B, Diederichs S. Gandhi M, et al. Nat Commun. 2020 Jun 25;11(1):3214. doi: 10.1038/s41467-020-17007-9. Nat Commun. 2020. PMID: 32587247 Free PMC article.

3

Mechanistic cross-talk between DNA/RNA polymerase enzyme kinetics and nucleotide substrate availability in cells: Implications for polymerase inhibitor discovery.

Coggins SA, Mahboubi B, Schinazi RF, Kim B. Coggins SA, et al. J Biol Chem. 2020 Sep 25;295(39):13432-13443. doi: 10.1074/jbc.REV120.013746. Epub 2020 Jul 31. J Biol Chem. 2020. PMID: 32737197 Free PMC article. Review.

4

Tetraspanin CD81 regulates HSV-1 infection.

Benayas B, Sastre I, López-Martín S, Oo A, Kim B, Bullido MJ, Aldudo J, Yáñez-Mó M. Benayas B, et al. Med Microbiol Immunol. 2020 Aug;209(4):489-498. doi: 10.1007/s00430-020-00684-0. Epub 2020 Jun 4. Med Microbiol Immunol. 2020. PMID: 32500359 Free PMC article.

5

Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.

Basbous J, Aze A, Chaloin L, Lebdy R, Hodroj D, Ribeyre C, Larroque M, Shepard C, Kim B, Pruvost A, Moreaux J, Maiorano D, Mechali M, Constantinou A. Basbous J, et al. Nucleic Acids Res. 2020 Feb 28;48(4):1886-1904. doi: 10.1093/nar/gkz1162. Nucleic Acids Res. 2020. PMID: 31853544 Free PMC article.

6

Novel Insights into the Molecular Regulation of Ribonucleotide Reductase in Adrenocortical Carcinoma Treatment.

Bothou C, Sharma A, Oo A, Kim B, Perge P, Igaz P, Ronchi CL, Shapiro I, Hantel C. Bothou C, et al. Cancers (Basel). 2021 Aug 20;13(16):4200. doi: 10.3390/cancers13164200. Cancers (Basel). 2021. PMID: 34439352 Free PMC article.

7

Enhanced enzyme kinetics of reverse transcriptase variants cloned from animals infected with SIVmac239 lacking viral protein X.

Coggins SA, Kim DH, Schinazi RF, Desrosier RC, Kim B. Coggins SA, et al. J Biol Chem. 2020 Dec 11;295(50):16975-16986. doi: 10.1074/jbc.RA120.015273. Epub 2020 Oct 2. J Biol Chem. 2020. PMID: 33008888 Free PMC article.

8

The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity.

Prasad CB, Oo A, Qiu Z, Li N, Singh D, Xin X, Cho YJ, Li Z, Zhang X, Yan C, Zheng Q, Shao J, Wang QE, Kim B, Zhang J. Prasad CB, et al. Res Sq [Preprint]. 2023 May 2:rs.3.rs-2814118. doi: 10.21203/rs.3.rs-2814118/v1. Res Sq. 2023. Update in: Nat Commun. 2024 May 31;15(1):4667. doi: 10.1038/s41467-024-48076-9 PMID: 37205570 Free PMC article. Updated. Preprint.

9

Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine.

Balachander S, Gombolay AL, Yang T, Xu P, Newnam G, Keskin H, El-Sayed WMM, Bryksin AV, Tao S, Bowen NE, Schinazi RF, Kim B, Koh KD, Vannberg FO, Storici F. Balachander S, et al. Nat Commun. 2020 May 15;11(1):2447. doi: 10.1038/s41467-020-16152-5. Nat Commun. 2020. PMID: 32415081 Free PMC article.

10

The dNTPase activity of SAMHD1 is important for its suppression of innate immune responses in differentiated monocytic cells.

Qin Z, Bonifati S, St Gelais C, Li TW, Kim SH, Antonucci JM, Mahboubi B, Yount JS, Xiong Y, Kim B, Wu L. Qin Z, et al. J Biol Chem. 2020 Feb 7;295(6):1575-1586. doi: 10.1074/jbc.RA119.010360. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914403 Free PMC article.

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