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Optimization of B-Ring-Functionalized Antimalarial Tambjamines and Prodiginines.
Kumar A, Chithanna S, Li Y, Zhang X, Dodean RA, Caridha D, Madejczyk MS, Lee PJ, Jin X, Chetree R, Blount C, Dennis WE, DeLuca J, Vuong C, Pannone K, Dinh HT, Leed S, Roth A, Reynolds KA, Kelly JX, Kancharla P. Kumar A, et al. J Med Chem. 2024 Nov 14;67(21):19755-19776. doi: 10.1021/acs.jmedchem.4c02093. Epub 2024 Oct 19. J Med Chem. 2024. PMID: 39425665 Free PMC article.
Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.
Kancharla P, Ortiz D, Fargo CM, Zhang X, Li Y, Sanchez M, Kumar A, Yeluguri M, Dodean RA, Caridha D, Madejczyk MS, Martin M, Jin X, Blount C, Chetree R, Pannone K, Dinh HT, DeLuca J, Evans M, Nadeau R, Vuong C, Leed S, Dennis WE, Roncal N, Pybus BS, Lee PJ, Roth A, Reynolds KA, Kelly JX, Landfear SM. Kancharla P, et al. J Med Chem. 2024 May 23;67(10):8323-8345. doi: 10.1021/acs.jmedchem.4c00517. Epub 2024 May 9. J Med Chem. 2024. PMID: 38722757 Free PMC article.