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42 results

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Page 1
The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.
Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, Rao A. Martinez GJ, et al. Immunity. 2015 Feb 17;42(2):265-278. doi: 10.1016/j.immuni.2015.01.006. Epub 2015 Feb 10. Immunity. 2015. PMID: 25680272 Free PMC article.
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion.
Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM. Hope JL, et al. Cell Rep. 2023 May 30;42(5):112436. doi: 10.1016/j.celrep.2023.112436. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37115668 Free PMC article.
Defining 'T cell exhaustion'.
Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D. Blank CU, et al. Nat Rev Immunol. 2019 Nov;19(11):665-674. doi: 10.1038/s41577-019-0221-9. Epub 2019 Sep 30. Nat Rev Immunol. 2019. PMID: 31570879 Free PMC article. Review.
STIM calcium sensing and conformational change.
Gudlur A, Zeraik AE, Hirve N, Hogan PG. Gudlur A, et al. J Physiol. 2020 May;598(9):1695-1705. doi: 10.1113/JP276524. Epub 2019 Jul 11. J Physiol. 2020. PMID: 31228261 Free PMC article. Review.
Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput.
Kennedy PH, Alborzian Deh Sheikh A, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer CG, Alarcón S, Newby GA, Myers SA. Kennedy PH, et al. Nat Methods. 2024 Jun;21(6):1033-1043. doi: 10.1038/s41592-024-02256-z. Epub 2024 Apr 29. Nat Methods. 2024. PMID: 38684783
Calcineurin: A star is reborn.
Li H, Hogan PG. Li H, et al. Cell Calcium. 2021 Mar;94:102324. doi: 10.1016/j.ceca.2020.102324. Epub 2021 Jan 12. Cell Calcium. 2021. PMID: 33482473 Free PMC article.
42 results