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Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.
DeMichele-Sweet MAA, Klei L, Creese B, Harwood JC, Weamer EA, McClain L, Sims R, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Alarcón-Martín E, Valero S; NIA-LOAD Family Based Study Consortium, Alzheimer’s Disease Genetics Consortium (ADGC); Liu Y, Hooli B, Aarsland D, Selbaek G, Bergh S, Rongve A, Saltvedt I, Skjellegrind HK, Engdahl B, Stordal E, Andreassen OA, Djurovic S, Athanasiu L, Seripa D, Borroni B, Albani D, Forloni G, Mecocci P, Serretti A, De Ronchi D, Politis A, Williams J, Mayeux R, Foroud T, Ruiz A, Ballard C, Holmans P, Lopez OL, Kamboh MI, Devlin B, Sweet RA. DeMichele-Sweet MAA, et al. Mol Psychiatry. 2021 Oct;26(10):5797-5811. doi: 10.1038/s41380-021-01152-8. Epub 2021 Jun 10. Mol Psychiatry. 2021. PMID: 34112972 Free PMC article.
Genetic associations with psychosis and affective disturbance in Alzheimer's disease.
Antonsdottir IM, Creese B, Klei L, DeMichele-Sweet MAA, Weamer EA, Garcia-Gonzalez P, Marquie M, Boada M, Alarcón-Martín E, Valero S; NIA‐LOAD Family Based Study Consortium, Alzheimer's Disease Genetics Consortium (ADGC), AddNeuroMed Consortium; Liu Y, Hooli B, Aarsland D, Selbaek G, Bergh S, Rongve A, Saltvedt I, Skjellegrind HK, Engdahl B, Andreassen OA, Borroni B, Mecocci P, Wedatilake Y, Mayeux R, Foroud T, Ruiz A, Lopez OL, Kamboh MI, Ballard C, Devlin B, Lyketsos C, Sweet RA. Antonsdottir IM, et al. Alzheimers Dement (N Y). 2024 May 23;10(2):e12472. doi: 10.1002/trc2.12472. eCollection 2024 Apr-Jun. Alzheimers Dement (N Y). 2024. PMID: 38784964 Free PMC article.
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
Smith RG, Pishva E, Shireby G, Smith AR, Roubroeks JAY, Hannon E, Wheildon G, Mastroeni D, Gasparoni G, Riemenschneider M, Giese A, Sharp AJ, Schalkwyk L, Haroutunian V, Viechtbauer W, van den Hove DLA, Weedon M, Brokaw D, Francis PT, Thomas AJ, Love S, Morgan K, Walter J, Coleman PD, Bennett DA, De Jager PL, Mill J, Lunnon K. Smith RG, et al. Nat Commun. 2021 Jun 10;12(1):3517. doi: 10.1038/s41467-021-23243-4. Nat Commun. 2021. PMID: 34112773 Free PMC article.
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study.
Smith RG, Pishva E, Kouhsar M, Imm J, Dobricic V, Johannsen P, Wittig M, Franke A, Vandenberghe R, Schaeverbeke J, Freund-Levi Y, Frölich L, Scheltens P, Teunissen CE, Frisoni G, Blin O, Richardson JC, Bordet R, Engelborghs S, de Roeck E, Martinez-Lage P, Altuna M, Tainta M, Lleó A, Sala I, Popp J, Peyratout G, Winchester L, Nevado-Holgado A, Verhey F, Tsolaki M, Andreasson U, Blennow K, Zetterberg H, Streffer J, Vos SJB, Lovestone S, Visser PJ, Bertram L, Lunnon K. Smith RG, et al. Alzheimers Dement. 2024 Oct;20(10):6722-6739. doi: 10.1002/alz.14098. Epub 2024 Aug 28. Alzheimers Dement. 2024. PMID: 39193893 Free PMC article.