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Page 1
Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.
Englund DA, Jolliffe AM, Hanson GJ, Aversa Z, Zhang X, Jiang X, White TA, Zhang L, Monroe DG, Robbins PD, Niedernhofer LJ, Kamenecka TM, Khosla S, LeBrasseur NK. Englund DA, et al. JCI Insight. 2024 Jan 23;9(2):e169512. doi: 10.1172/jci.insight.169512. JCI Insight. 2024. PMID: 38051584 Free PMC article.
p21 induces a senescence program and skeletal muscle dysfunction.
Englund DA, Jolliffe A, Aversa Z, Zhang X, Sturmlechner I, Sakamoto AE, Zeidler JD, Warner GM, McNinch C, White TA, Chini EN, Baker DJ, van Deursen JM, LeBrasseur NK. Englund DA, et al. Mol Metab. 2023 Jan;67:101652. doi: 10.1016/j.molmet.2022.101652. Epub 2022 Dec 9. Mol Metab. 2023. PMID: 36509362 Free PMC article.
Biomarkers of cellular senescence and risk of death in humans.
St Sauver JL, Weston SA, Atkinson EJ, Mc Gree ME, Mielke MM, White TA, Heeren AA, Olson JE, Rocca WA, Palmer AK, Cummings SR, Fielding RA, Bielinski SJ, LeBrasseur NK. St Sauver JL, et al. Aging Cell. 2023 Dec;22(12):e14006. doi: 10.1111/acel.14006. Epub 2023 Oct 6. Aging Cell. 2023. PMID: 37803875 Free PMC article.
Calorie restriction reduces biomarkers of cellular senescence in humans.
Aversa Z, White TA, Heeren AA, Hulshizer CA, Saul D, Zhang X, Molina AJA, Redman LM, Martin CK, Racette SB, Huffman KM, Bhapkar M, Khosla S, Das SK, Fielding RA, Atkinson EJ, LeBrasseur NK. Aversa Z, et al. Aging Cell. 2024 Feb;23(2):e14038. doi: 10.1111/acel.14038. Epub 2023 Nov 14. Aging Cell. 2024. PMID: 37961856 Free PMC article.
BMAL1 modulates senescence programming via AP-1.
Jachim SK, Zhong J, Ordog T, Lee JH, Bhagwate AV, Nagaraj NK, Westendorf JJ, Passos JF, Matveyenko AV, LeBrasseur NK. Jachim SK, et al. Aging (Albany NY). 2023 Oct 10;15(19):9984-10009. doi: 10.18632/aging.205112. Epub 2023 Oct 10. Aging (Albany NY). 2023. PMID: 37819791 Free PMC article.
Distinct secretomes in p16- and p21- positive senescent cells across tissues.
Saul D, Jurk D, Doolittle ML, Kosinsky RL, Monroe DG, LeBrasseur NK, Robbins PD, Niedernhofer LJ, Khosla S, Passos JF. Saul D, et al. bioRxiv [Preprint]. 2023 Dec 5:2023.12.05.569858. doi: 10.1101/2023.12.05.569858. bioRxiv. 2023. PMID: 38106149 Free PMC article. Preprint.
Hungry for biomarkers of aging.
LeBrasseur NK. LeBrasseur NK. Aging Cell. 2024 Apr;23(4):e14158. doi: 10.1111/acel.14158. Epub 2024 Mar 27. Aging Cell. 2024. PMID: 38532727 Free PMC article. No abstract available.
Characterization of cellular senescence in aging skeletal muscle.
Zhang X, Habiballa L, Aversa Z, Ng YE, Sakamoto AE, Englund DA, Pearsall VM, White TA, Robinson MM, Rivas DA, Dasari S, Hruby AJ, Lagnado AB, Jachim SK, Granic A, Sayer AA, Jurk D, Lanza IR, Khosla S, Fielding RA, Nair KS, Schafer MJ, Passos JF, LeBrasseur NK. Zhang X, et al. Nat Aging. 2022 Jul;2(7):601-615. doi: 10.1038/s43587-022-00250-8. Epub 2022 Jul 15. Nat Aging. 2022. PMID: 36147777 Free PMC article.
23 results