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Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo.
Biochem J. 2022 Feb 11;479(3):401-424. doi: 10.1042/BCJ20210615.
Biochem J. 2022.
PMID: 35147166
Free PMC article.
The anti-cancer drug dabrafenib is not cardiotoxic and inhibits cardiac remodelling and fibrosis in a murine model of hypertension.
Meijles DN, Cull JJ, Cooper STE, Markou T, Hardyman MA, Fuller SJ, Alharbi HO, Haines ZHR, Alcantara-Alonso V, Glennon PE, Sheppard MN, Sugden PH, Clerk A.
Meijles DN, et al.
Clin Sci (Lond). 2021 Jul 30;135(14):1631-1647. doi: 10.1042/CS20210192.
Clin Sci (Lond). 2021.
PMID: 34296750
Free PMC article.
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