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Page 1
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma.
Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, Schuster SJ, Millenson MM, Cattry D, Freeman GJ, Rodig SJ, Chapuy B, Ligon AH, Zhu L, Grosso JF, Kim SY, Timmerman JM, Shipp MA, Armand P. Ansell SM, et al. N Engl J Med. 2015 Jan 22;372(4):311-9. doi: 10.1056/NEJMoa1411087. Epub 2014 Dec 6. N Engl J Med. 2015. PMID: 25482239 Free PMC article. Clinical Trial.
NF-κB regulates PD-1 expression in macrophages.
Bally AP, Lu P, Tang Y, Austin JW, Scharer CD, Ahmed R, Boss JM. Bally AP, et al. J Immunol. 2015 May 1;194(9):4545-54. doi: 10.4049/jimmunol.1402550. Epub 2015 Mar 25. J Immunol. 2015. PMID: 25810391 Free PMC article.
Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.
Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Joller N, et al. J Immunol. 2011 Feb 1;186(3):1338-42. doi: 10.4049/jimmunol.1003081. Epub 2011 Jan 3. J Immunol. 2011. PMID: 21199897 Free PMC article.
18 results