NS089616/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	1
2017	3
2018	4
2019	4
2020	3
2021	5
2022	2
2023	2
2024	2

1

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.

Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, Daley EL, Miller SJ, Cunningham KM, Vidensky S, Gupta S, Thomas MA, Hong I, Chiu SL, Huganir RL, Ostrow LW, Matunis MJ, Wang J, Sattler R, Lloyd TE, Rothstein JD. Zhang K, et al. Nature. 2015 Sep 3;525(7567):56-61. doi: 10.1038/nature14973. Epub 2015 Aug 26. Nature. 2015. PMID: 26308891 Free PMC article.

2

C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly.

Wang T, Liu H, Itoh K, Oh S, Zhao L, Murata D, Sesaki H, Hartung T, Na CH, Wang J. Wang T, et al. Cell Metab. 2021 Mar 2;33(3):531-546.e9. doi: 10.1016/j.cmet.2021.01.005. Epub 2021 Feb 4. Cell Metab. 2021. PMID: 33545050 Free PMC article.

3

G-Quadruplexes as pathogenic drivers in neurodegenerative disorders.

Wang E, Thombre R, Shah Y, Latanich R, Wang J. Wang E, et al. Nucleic Acids Res. 2021 May 21;49(9):4816-4830. doi: 10.1093/nar/gkab164. Nucleic Acids Res. 2021. PMID: 33784396 Free PMC article. Review.

4

NDST3 deacetylates α-tubulin and suppresses V-ATPase assembly and lysosomal acidification.

Tang Q, Liu M, Liu Y, Hwang RD, Zhang T, Wang J. Tang Q, et al. EMBO J. 2021 Oct 1;40(19):e107204. doi: 10.15252/embj.2020107204. Epub 2021 Aug 25. EMBO J. 2021. PMID: 34435379 Free PMC article.

5

Autophagy as a common pathway in amyotrophic lateral sclerosis.

Nguyen DKH, Thombre R, Wang J. Nguyen DKH, et al. Neurosci Lett. 2019 Apr 1;697:34-48. doi: 10.1016/j.neulet.2018.04.006. Epub 2018 Apr 4. Neurosci Lett. 2019. PMID: 29626651 Free PMC article. Review.

6

Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules.

Wang T, Tian X, Kim HB, Jang Y, Huang Z, Na CH, Wang J. Wang T, et al. Nat Commun. 2022 Sep 23;13(1):5584. doi: 10.1038/s41467-022-33079-1. Nat Commun. 2022. PMID: 36151083 Free PMC article.

7

CRISPR/Cas13d targeting suppresses repeat-associated non-AUG translation of C9orf72 hexanucleotide repeat RNA.

Liu H, Zhao XF, Lu YN, Hayes LR, Wang J. Liu H, et al. J Clin Invest. 2024 Sep 17;134(21):e179016. doi: 10.1172/JCI179016. J Clin Invest. 2024. PMID: 39288267 Free PMC article.

8

DNA-initiated epigenetic cascades driven by C9orf72 hexanucleotide repeat.

Liu Y, Huang Z, Liu H, Ji Z, Arora A, Cai D, Wang H, Liu M, Simko EAJ, Zhang Y, Periz G, Liu Z, Wang J. Liu Y, et al. Neuron. 2023 Apr 19;111(8):1205-1221.e9. doi: 10.1016/j.neuron.2023.01.022. Epub 2023 Feb 22. Neuron. 2023. PMID: 36822200 Free PMC article.

9

DNA-initiated epigenetic cascades driven by C9orf72 hexanucleotide repeat.

Liu Y, Huang Z, Liu H, Ji Z, Arora A, Cai D, Wang H, Liu M, Simko EAJ, Zhang Y, Periz G, Liu Z, Wang J. Liu Y, et al. Neuron. 2023 Apr 19;111(8):1345. doi: 10.1016/j.neuron.2023.03.035. Neuron. 2023. PMID: 37080168 Free PMC article. No abstract available.

10

L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control.

Lu J, Periz G, Lu YN, Tang Q, Liu Y, Zhang T, Shah Y, Thombre R, Aljumaah R, Li W, Mojsilovic-Petrovic J, Ji Y, Johnson K, Kalb R, Wang J. Lu J, et al. Nat Neurosci. 2019 Jun;22(6):875-886. doi: 10.1038/s41593-019-0384-5. Epub 2019 May 6. Nat Neurosci. 2019. PMID: 31061493 Free PMC article.

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