NS-50210/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2006	1
2008	3
2009	3
2010	1
2011	3
2013	1
2024	0

1

RNA polymerase III transcribes human microRNAs.

Borchert GM, Lanier W, Davidson BL. Borchert GM, et al. Nat Struct Mol Biol. 2006 Dec;13(12):1097-101. doi: 10.1038/nsmb1167. Epub 2006 Nov 12. Nat Struct Mol Biol. 2006. PMID: 17099701

2

Splice isoform-specific suppression of the Cav2.1 variant underlying spinocerebellar ataxia type 6.

Tsou WL, Soong BW, Paulson HL, Rodríguez-Lebrón E. Tsou WL, et al. Neurobiol Dis. 2011 Sep;43(3):533-42. doi: 10.1016/j.nbd.2011.04.016. Epub 2011 Apr 29. Neurobiol Dis. 2011. PMID: 21550405 Free PMC article.

3

Altered Purkinje cell miRNA expression and SCA1 pathogenesis.

Rodriguez-Lebron E, Liu G, Keiser M, Behlke MA, Davidson BL. Rodriguez-Lebron E, et al. Neurobiol Dis. 2013 Jun;54:456-63. doi: 10.1016/j.nbd.2013.01.019. Epub 2013 Jan 30. Neurobiol Dis. 2013. PMID: 23376683 Free PMC article.

4

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs.

Boudreau RL, Monteys AM, Davidson BL. Boudreau RL, et al. RNA. 2008 Sep;14(9):1834-44. doi: 10.1261/rna.1062908. Epub 2008 Aug 12. RNA. 2008. PMID: 18697922 Free PMC article.

5

Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.

Boudreau RL, McBride JL, Martins I, Shen S, Xing Y, Carter BJ, Davidson BL. Boudreau RL, et al. Mol Ther. 2009 Jun;17(6):1053-63. doi: 10.1038/mt.2009.17. Epub 2009 Feb 24. Mol Ther. 2009. PMID: 19240687 Free PMC article.

6

Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease.

Rodríguez-Lebrón E, Gouvion CM, Moore SA, Davidson BL, Paulson HL. Rodríguez-Lebrón E, et al. Mol Ther. 2009 Sep;17(9):1563-73. doi: 10.1038/mt.2009.123. Epub 2009 Jun 16. Mol Ther. 2009. PMID: 19532137 Free PMC article.

7

Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo.

Boudreau RL, Martins I, Davidson BL. Boudreau RL, et al. Mol Ther. 2009 Jan;17(1):169-75. doi: 10.1038/mt.2008.231. Epub 2008 Nov 11. Mol Ther. 2009. PMID: 19002161 Free PMC article.

8

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi.

McBride JL, Boudreau RL, Harper SQ, Staber PD, Monteys AM, Martins I, Gilmore BL, Burstein H, Peluso RW, Polisky B, Carter BJ, Davidson BL. McBride JL, et al. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5868-73. doi: 10.1073/pnas.0801775105. Epub 2008 Apr 8. Proc Natl Acad Sci U S A. 2008. PMID: 18398004 Free PMC article.

9

Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington's disease.

Boudreau RL, Spengler RM, Davidson BL. Boudreau RL, et al. Mol Ther. 2011 Dec;19(12):2169-77. doi: 10.1038/mt.2011.185. Epub 2011 Sep 27. Mol Ther. 2011. PMID: 21952166 Free PMC article.

10

Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease.

McBride JL, Pitzer MR, Boudreau RL, Dufour B, Hobbs T, Ojeda SR, Davidson BL. McBride JL, et al. Mol Ther. 2011 Dec;19(12):2152-62. doi: 10.1038/mt.2011.219. Epub 2011 Oct 25. Mol Ther. 2011. PMID: 22031240 Free PMC article.

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