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19 results

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Page 1
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Robertson CC, Inshaw JRJ, Onengut-Gumuscu S, Chen WM, Santa Cruz DF, Yang H, Cutler AJ, Crouch DJM, Farber E, Bridges SL Jr, Edberg JC, Kimberly RP, Buckner JH, Deloukas P, Divers J, Dabelea D, Lawrence JM, Marcovina S, Shah AS, Greenbaum CJ, Atkinson MA, Gregersen PK, Oksenberg JR, Pociot F, Rewers MJ, Steck AK, Dunger DB; Type 1 Diabetes Genetics Consortium; Wicker LS, Concannon P, Todd JA, Rich SS. Robertson CC, et al. Nat Genet. 2021 Jul;53(7):962-971. doi: 10.1038/s41588-021-00880-5. Epub 2021 Jun 14. Nat Genet. 2021. PMID: 34127860 Free PMC article.
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
Hughes LB, Morrison D, Kelley JM, Padilla MA, Vaughan LK, Westfall AO, Dwivedi H, Mikuls TR, Holers VM, Parrish LA, Alarcón GS, Conn DL, Jonas BL, Callahan LF, Smith EA, Gilkeson GS, Howard G, Moreland LW, Patterson N, Reich D, Bridges SL Jr. Hughes LB, et al. Arthritis Rheum. 2008 Feb;58(2):349-58. doi: 10.1002/art.23166. Arthritis Rheum. 2008. PMID: 18240241 Free PMC article.
An African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans.
Kelley JM, Hughes LB, Faggard JD, Danila MI, Crawford MH, Edberg Y, Padilla MA, Tiwari HK, Westfall AO, Alarcón GS, Conn DL, Jonas BL, Callahan LF, Smith EA, Brasington RD, Allison DB, Kimberly RP, Moreland LW, Edberg JC, Bridges SL Jr. Kelley JM, et al. PLoS Genet. 2009 Mar;5(3):e1000424. doi: 10.1371/journal.pgen.1000424. Epub 2009 Mar 20. PLoS Genet. 2009. Retraction in: PLoS Genet. 2009 Dec;5(12). doi: 10.1371/annotation/80bd7285-9d2d-403a-8e6f-9c375bf977ca. PMID: 19300490 Free PMC article. Retracted.
Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans.
Kelley JM, Hughes LB, Malik A, Danila MI, Edberg Y, Alarcón GS, Conn DL, Jonas BL, Callahan LF, Smith EA, Brasington RD, Edberg JC, Kimberly RP, Moreland LW, Bridges SL. Kelley JM, et al. Ann Rheum Dis. 2010 Apr;69(4):625-6. doi: 10.1136/ard.2009.113183. Ann Rheum Dis. 2010. PMID: 20237121 Free PMC article. No abstract available.
Socioeconomic factors and self-reported health outcomes in African Americans with rheumatoid arthritis from the Southeastern United States: the contribution of childhood socioeconomic status.
Baldassari AR, Cleveland RJ, Luong MN, Jonas BL; Consortium for the Longitudinal Evaluation of African Americans with Early Rheumatoid Arthritis; Conn DL, Moreland LW, Bridges SL Jr, Callahan LF. Baldassari AR, et al. BMC Musculoskelet Disord. 2016 Jan 12;17:10. doi: 10.1186/s12891-016-0882-5. BMC Musculoskelet Disord. 2016. PMID: 26754747 Free PMC article.
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