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A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
Nat Med. 2023 Jul;29(7):1793-1803. doi: 10.1038/s41591-023-02429-x. Epub 2023 Jul 6.
Nat Med. 2023.
PMID: 37414900
Free PMC article.
ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon.
Hartmann S, Yasmeen S, Jacobs BM, Denaxas S, Pirmohamed M, Gamazon ER, Caulfield MJ; Genes & Health Research Team; Hemingway H, Pietzner M, Langenberg C.
Hartmann S, et al.
Nat Commun. 2023 Oct 12;14(1):6156. doi: 10.1038/s41467-023-41876-5.
Nat Commun. 2023.
PMID: 37828025
Free PMC article.
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Influence of autozygosity on common disease risk across the phenotypic spectrum.
Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM, Khan A, Mirkov MU; 23andMe Research Team; Genes & Health Research Team; Kuwahara H, Gao X, Alkuraya FS, Posthuma D, Newman WG, Griffiths CJ, Mathur R, van Heel DA, Finer S, O'Connell J, Martin HC.
Malawsky DS, et al.
Cell. 2023 Oct 12;186(21):4514-4527.e14. doi: 10.1016/j.cell.2023.08.028. Epub 2023 Sep 26.
Cell. 2023.
PMID: 37757828
Free PMC article.
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CYP2C19 loss-of-function alleles are not associated with higher prevalence of gastrointestinal bleeds in those who have been prescribed antidepressants: Analysis in a British-South Asian cohort.
Magavern EF, van Heel DA; Genes & Health Research Team; Smedley D, Caulfield MJ.
Magavern EF, et al.
Br J Clin Pharmacol. 2023 Nov;89(11):3432-3438. doi: 10.1111/bcp.15762. Epub 2023 Aug 6.
Br J Clin Pharmacol. 2023.
PMID: 37143396
Free article.
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