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Page 1
HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation.
Vlachava VM, Seirafian S, Fielding CA, Kollnberger S, Aicheler RJ, Hughes J, Baker A, Weekes MP, Forbes S, Wilkinson GWG, Wang ECY, Stanton RJ. Vlachava VM, et al. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2309077120. doi: 10.1073/pnas.2309077120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011551 Free PMC article.
A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G; ISARIC4C Investigators; Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Wickenhagen A, et al. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. Science. 2021. PMID: 34581622 Free PMC article.
CD57+ Memory T Cells Proliferate In Vivo.
Ahmed R, Miners KL, Lahoz-Beneytez J, Jones RE, Roger L, Baboonian C, Zhang Y, Wang ECY, Hellerstein MK, McCune JM, Baird DM, Price DA, Macallan DC, Asquith B, Ladell K. Ahmed R, et al. Cell Rep. 2020 Dec 15;33(11):108501. doi: 10.1016/j.celrep.2020.108501. Cell Rep. 2020. PMID: 33326780 Free PMC article.
Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1.
Boelen L, Debebe B, Silveira M, Salam A, Makinde J, Roberts CH, Wang ECY, Frater J, Gilmour J, Twigger K, Ladell K, Miners KL, Jayaraman J, Traherne JA, Price DA, Qi Y, Martin MP, Macallan DC, Thio CL, Astemborski J, Kirk G, Donfield SM, Buchbinder S, Khakoo SI, Goedert JJ, Trowsdale J, Carrington M, Kollnberger S, Asquith B. Boelen L, et al. Sci Immunol. 2018 Nov 9;3(29):eaao2892. doi: 10.1126/sciimmunol.aao2892. Sci Immunol. 2018. PMID: 30413420 Free PMC article.
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor.
Fletcher-Etherington A, Nobre L, Nightingale K, Antrobus R, Nichols J, Davison AJ, Stanton RJ, Weekes MP. Fletcher-Etherington A, et al. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18771-18779. doi: 10.1073/pnas.2001887117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690704 Free PMC article.
ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.
Rubina A, Patel M, Nightingale K, Potts M, Fielding CA, Kollnberger S, Lau B, Ladell K, Miners KL, Nichols J, Nobre L, Roberts D, Trinca TM, Twohig JP, Vlahava VM, Davison AJ, Price DA, Tomasec P, Wilkinson GWG, Weekes MP, Stanton RJ, Wang ECY. Rubina A, et al. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2303155120. doi: 10.1073/pnas.2303155120. Epub 2023 Aug 10. Proc Natl Acad Sci U S A. 2023. PMID: 37561786 Free PMC article.
21 results