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Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer.
Kocher HM, Basu B, Froeling FEM, Sarker D, Slater S, Carlin D, deSouza NM, De Paepe KN, Goulart MR, Hughes C, Imrali A, Roberts R, Pawula M, Houghton R, Lawrence C, Yogeswaran Y, Mousa K, Coetzee C, Sasieni P, Prendergast A, Propper DJ. Kocher HM, et al. Nat Commun. 2020 Sep 24;11(1):4841. doi: 10.1038/s41467-020-18636-w. Nat Commun. 2020. PMID: 32973176 Free PMC article. Clinical Trial.