MR/L011093/1/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2015	2
2016	5
2017	3
2018	1
2019	2
2020	2
2021	4
2024	0

1

Regional protein expression in human Alzheimer's brain correlates with disease severity.

Xu J, Patassini S, Rustogi N, Riba-Garcia I, Hale BD, Phillips AM, Waldvogel H, Haines R, Bradbury P, Stevens A, Faull RLM, Dowsey AW, Cooper GJS, Unwin RD. Xu J, et al. Commun Biol. 2019 Feb 4;2:43. doi: 10.1038/s42003-018-0254-9. eCollection 2019. Commun Biol. 2019. PMID: 30729181 Free PMC article.

2

Metabolite mapping reveals severe widespread perturbation of multiple metabolic processes in Huntington's disease human brain.

Patassini S, Begley P, Xu J, Church SJ, Reid SJ, Kim EH, Curtis MA, Dragunow M, Waldvogel HJ, Snell RG, Unwin RD, Faull RL, Cooper GJ. Patassini S, et al. Biochim Biophys Acta. 2016 Sep;1862(9):1650-62. doi: 10.1016/j.bbadis.2016.06.002. Epub 2016 Jun 4. Biochim Biophys Acta. 2016. PMID: 27267344 Free article.

3

Metabolic Dysfunction Is Restricted to the Sciatic Nerve in Experimental Diabetic Neuropathy.

Freeman OJ, Unwin RD, Dowsey AW, Begley P, Ali S, Hollywood KA, Rustogi N, Petersen RS, Dunn WB, Cooper GJ, Gardiner NJ. Freeman OJ, et al. Diabetes. 2016 Jan;65(1):228-38. doi: 10.2337/db15-0835. Epub 2015 Oct 15. Diabetes. 2016. PMID: 26470786

4

Identification of elevated urea as a severe, ubiquitous metabolic defect in the brain of patients with Huntington's disease.

Patassini S, Begley P, Reid SJ, Xu J, Church SJ, Curtis M, Dragunow M, Waldvogel HJ, Unwin RD, Snell RG, Faull RL, Cooper GJ. Patassini S, et al. Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):161-6. doi: 10.1016/j.bbrc.2015.10.140. Epub 2015 Oct 30. Biochem Biophys Res Commun. 2015. PMID: 26522227

5

Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain.

Scholefield M, Church SJ, Xu J, Robinson AC, Gardiner NJ, Roncaroli F, Hooper NM, Unwin RD, Cooper GJS. Scholefield M, et al. Metabolites. 2020 Oct 29;10(11):438. doi: 10.3390/metabo10110438. Metabolites. 2020. PMID: 33138273 Free PMC article.

6

Expanding the Use of Spectral Libraries in Proteomics.

Deutsch EW, Perez-Riverol Y, Chalkley RJ, Wilhelm M, Tate S, Sachsenberg T, Walzer M, Käll L, Delanghe B, Böcker S, Schymanski EL, Wilmes P, Dorfer V, Kuster B, Volders PJ, Jehmlich N, Vissers JPC, Wolan DW, Wang AY, Mendoza L, Shofstahl J, Dowsey AW, Griss J, Salek RM, Neumann S, Binz PA, Lam H, Vizcaíno JA, Bandeira N, Röst H. Deutsch EW, et al. J Proteome Res. 2018 Dec 7;17(12):4051-4060. doi: 10.1021/acs.jproteome.8b00485. Epub 2018 Oct 11. J Proteome Res. 2018. PMID: 30270626 Free PMC article. Review.

7

Widespread Decreases in Cerebral Copper Are Common to Parkinson's Disease Dementia and Alzheimer's Disease Dementia.

Scholefield M, Church SJ, Xu J, Patassini S, Roncaroli F, Hooper NM, Unwin RD, Cooper GJS. Scholefield M, et al. Front Aging Neurosci. 2021 Mar 3;13:641222. doi: 10.3389/fnagi.2021.641222. eCollection 2021. Front Aging Neurosci. 2021. PMID: 33746735 Free PMC article.

8

Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia.

Xu J, Church SJ, Patassini S, Begley P, Waldvogel HJ, Curtis MA, Faull RLM, Unwin RD, Cooper GJS. Xu J, et al. Metallomics. 2017 Aug 16;9(8):1106-1119. doi: 10.1039/c7mt00074j. Metallomics. 2017. PMID: 28654115

9

Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice.

Aitken JF, Loomes KM, Riba-Garcia I, Unwin RD, Prijic G, Phillips AS, Phillips ARJ, Wu D, Poppitt SD, Ding K, Barran PE, Dowsey AW, Cooper GJS. Aitken JF, et al. Biochem Biophys Res Commun. 2017 Jan 22;482(4):625-631. doi: 10.1016/j.bbrc.2016.11.083. Epub 2016 Nov 16. Biochem Biophys Res Commun. 2017. PMID: 27865831

10

Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigation.

Kassab S, Begley P, Church SJ, Rotariu SM, Chevalier-Riffard C, Dowsey AW, Phillips AM, Zeef LAH, Grayson B, Neill JC, Cooper GJS, Unwin RD, Gardiner NJ. Kassab S, et al. Mol Metab. 2019 Oct;28:107-119. doi: 10.1016/j.molmet.2019.08.003. Epub 2019 Aug 5. Mol Metab. 2019. PMID: 31451429 Free PMC article.

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