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Page 1
Circadian rhythm of exhaled biomarkers in health and asthma.
Wilkinson M, Maidstone R, Loudon A, Blaikley J, White IR, Singh D, Ray DW, Goodacre R, Fowler SJ, Durrington HJ. Wilkinson M, et al. Eur Respir J. 2019 Oct 17;54(4):1901068. doi: 10.1183/13993003.01068-2019. Print 2019 Oct. Eur Respir J. 2019. PMID: 31221808 Free PMC article.
Night shift work is associated with an increased risk of asthma.
Maidstone RJ, Turner J, Vetter C, Dashti HS, Saxena R, Scheer FAJL, Shea SA, Kyle SD, Lawlor DA, Loudon ASI, Blaikley JF, Rutter MK, Ray DW, Durrington HJ. Maidstone RJ, et al. Thorax. 2021 Jan;76(1):53-60. doi: 10.1136/thoraxjnl-2020-215218. Epub 2020 Nov 16. Thorax. 2021. PMID: 33199525 Free PMC article.
Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion.
Zhang Z, Hunter L, Wu G, Maidstone R, Mizoro Y, Vonslow R, Fife M, Hopwood T, Begley N, Saer B, Wang P, Cunningham P, Baxter M, Durrington H, Blaikley JF, Hussell T, Rattray M, Hogenesch JB, Gibbs J, Ray DW, Loudon ASI. Zhang Z, et al. FASEB J. 2019 May;33(5):6226-6238. doi: 10.1096/fj.201801682R. Epub 2019 Feb 22. FASEB J. 2019. PMID: 30794439 Free PMC article.
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Kitchen GB, Cunningham PS, Poolman TM, Iqbal M, Maidstone R, Baxter M, Bagnall J, Begley N, Saer B, Hussell T, Matthews LC, Dockrell DH, Durrington HJ, Gibbs JE, Blaikley JF, Loudon AS, Ray DW. Kitchen GB, et al. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1543-1551. doi: 10.1073/pnas.1915932117. Epub 2020 Jan 3. Proc Natl Acad Sci U S A. 2020. PMID: 31900362 Free PMC article.
Circadian asthma airway responses are gated by REV-ERBα.
Durrington HJ, Krakowiak K, Meijer P, Begley N, Maidstone R, Goosey L, Gibbs JE, Blaikley JF, Gregory LG, Lloyd CM, Loudon ASI, Ray DW. Durrington HJ, et al. Eur Respir J. 2020 Dec 17;56(6):1902407. doi: 10.1183/13993003.02407-2019. Print 2020 Dec. Eur Respir J. 2020. PMID: 32586876 Free PMC article.
15 results