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Increased alcohol dehydrogenase 1 activity promotes longevity.
Ghaddar A, Mony VK, Mishra S, Berhanu S, Johnson JC, Enriquez-Hesles E, Harrison E, Patel A, Horak MK, Smith JS, O'Rourke EJ. Ghaddar A, et al. Curr Biol. 2023 Mar 27;33(6):1036-1046.e6. doi: 10.1016/j.cub.2023.01.059. Epub 2023 Feb 17. Curr Biol. 2023. PMID: 36805847 Free PMC article.
Genes in human obesity loci are causal obesity genes in C. elegans.
Ke W, Reed JN, Yang C, Higgason N, Rayyan L, Wählby C, Carpenter AE, Civelek M, O'Rourke EJ. Ke W, et al. PLoS Genet. 2021 Sep 7;17(9):e1009736. doi: 10.1371/journal.pgen.1009736. eCollection 2021 Sep. PLoS Genet. 2021. PMID: 34492009 Free PMC article.
Whole-body gene expression atlas of an adult metazoan.
Ghaddar A, Armingol E, Huynh C, Gevirtzman L, Lewis NE, Waterston R, O'Rourke EJ. Ghaddar A, et al. Sci Adv. 2023 Jun 23;9(25):eadg0506. doi: 10.1126/sciadv.adg0506. Epub 2023 Jun 23. Sci Adv. 2023. PMID: 37352352 Free PMC article.
An image analysis toolbox for high-throughput C. elegans assays.
Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE. Wählby C, et al. Nat Methods. 2012 Apr 22;9(7):714-6. doi: 10.1038/nmeth.1984. Nat Methods. 2012. PMID: 22522656 Free PMC article.