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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. Shimada K, et al. Immunity. 2012 Mar 23;36(3):401-14. doi: 10.1016/j.immuni.2012.01.009. Epub 2012 Feb 16. Immunity. 2012. PMID: 22342844 Free PMC article.
The stumpy gene is required for mammalian ciliogenesis.
Town T, Breunig JJ, Sarkisian MR, Spilianakis C, Ayoub AE, Liu X, Ferrandino AF, Gallagher AR, Li MO, Rakic P, Flavell RA. Town T, et al. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2853-8. doi: 10.1073/pnas.0712385105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287022 Free PMC article.
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