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Page 1
A systems approach to infectious disease.
Eckhardt M, Hultquist JF, Kaake RM, Hüttenhain R, Krogan NJ. Eckhardt M, et al. Nat Rev Genet. 2020 Jun;21(6):339-354. doi: 10.1038/s41576-020-0212-5. Epub 2020 Feb 14. Nat Rev Genet. 2020. PMID: 32060427 Free PMC article. Review.
Molecular epidemiology in the HIV and SARS-CoV-2 pandemics.
Lorenzo-Redondo R, Ozer EA, Achenbach CJ, D'Aquila RT, Hultquist JF. Lorenzo-Redondo R, et al. Curr Opin HIV AIDS. 2021 Jan;16(1):11-24. doi: 10.1097/COH.0000000000000660. Curr Opin HIV AIDS. 2021. PMID: 33186230 Free PMC article. Review.
Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.
Martin-Sancho L, Tripathi S, Rodriguez-Frandsen A, Pache L, Sanchez-Aparicio M, McGregor MJ, Haas KM, Swaney DL, Nguyen TT, Mamede JI, Churas C, Pratt D, Rosenthal SB, Riva L, Nguyen C, Beltran-Raygoza N, Soonthornvacharin S, Wang G, Jimenez-Morales D, De Jesus PD, Moulton HM, Stein DA, Chang MW, Benner C, Ideker T, Albrecht RA, Hultquist JF, Krogan NJ, García-Sastre A, Chanda SK. Martin-Sancho L, et al. Nat Microbiol. 2021 Oct;6(10):1319-1333. doi: 10.1038/s41564-021-00964-2. Epub 2021 Sep 23. Nat Microbiol. 2021. PMID: 34556855 Free PMC article.
A Unique Clade of SARS-CoV-2 Viruses is Associated with Lower Viral Loads in Patient Upper Airways.
Lorenzo-Redondo R, Nam HH, Roberts SC, Simons LM, Jennings LJ, Qi C, Achenbach CJ, Hauser AR, Ison MG, Hultquist JF, Ozer EA. Lorenzo-Redondo R, et al. medRxiv [Preprint]. 2020 Jun 21:2020.05.19.20107144. doi: 10.1101/2020.05.19.20107144. medRxiv. 2020. Update in: EBioMedicine. 2020 Dec;62:103112. doi: 10.1016/j.ebiom.2020.103112. PMID: 32511558 Free PMC article. Updated. Preprint.
ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.
Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ. Hüttenhain R, et al. Cell Host Microbe. 2019 Jul 10;26(1):86-99.e7. doi: 10.1016/j.chom.2019.05.008. Epub 2019 Jun 25. Cell Host Microbe. 2019. PMID: 31253590 Free PMC article.
A functional map of HIV-host interactions in primary human T cells.
Hiatt J, Hultquist JF, McGregor MJ, Bouhaddou M, Leenay RT, Simons LM, Young JM, Haas P, Roth TL, Tobin V, Wojcechowskyj JA, Woo JM, Rathore U, Cavero DA, Shifrut E, Nguyen TT, Haas KM, Malik HS, Doudna JA, May AP, Marson A, Krogan NJ. Hiatt J, et al. Nat Commun. 2022 Apr 1;13(1):1752. doi: 10.1038/s41467-022-29346-w. Nat Commun. 2022. PMID: 35365639 Free PMC article.
Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.
Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J. Leenay RT, et al. Nat Biotechnol. 2019 Sep;37(9):1034-1037. doi: 10.1038/s41587-019-0203-2. Epub 2019 Jul 29. Nat Biotechnol. 2019. PMID: 31359007 Free PMC article.
CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.
Chen SH, Jang GM, Hüttenhain R, Gordon DE, Du D, Newton BW, Johnson JR, Hiatt J, Hultquist JF, Johnson TL, Liu YL, Burton LA, Ye J, Reichermeier KM, Stroud RM, Marson A, Debnath J, Gross JD, Krogan NJ. Chen SH, et al. EMBO J. 2018 Sep 14;37(18):e97508. doi: 10.15252/embj.201797508. Epub 2018 Aug 30. EMBO J. 2018. PMID: 30166453 Free PMC article.
13 results