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2022 3
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Deciphering the immunopeptidome in vivo reveals new tumour antigens.
Jaeger AM, Stopfer LE, Ahn R, Sanders EA, Sandel DA, Freed-Pastor WA, Rideout WM 3rd, Naranjo S, Fessenden T, Nguyen KB, Winter PS, Kohn RE, Westcott PMK, Schenkel JM, Shanahan SL, Shalek AK, Spranger S, White FM, Jacks T. Jaeger AM, et al. Nature. 2022 Jul;607(7917):149-155. doi: 10.1038/s41586-022-04839-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705813 Free PMC article.
A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Ely ZA, Mathey-Andrews N, Naranjo S, Gould SI, Mercer KL, Newby GA, Cabana CM, Rideout WM 3rd, Jaramillo GC, Khirallah JM, Holland K, Randolph PB, Freed-Pastor WA, Davis JR, Kulstad Z, Westcott PMK, Lin L, Anzalone AV, Horton BL, Pattada NB, Shanahan SL, Ye Z, Spranger S, Xu Q, Sánchez-Rivera FJ, Liu DR, Jacks T. Ely ZA, et al. Nat Biotechnol. 2024 Mar;42(3):424-436. doi: 10.1038/s41587-023-01783-y. Epub 2023 May 11. Nat Biotechnol. 2024. PMID: 37169967 Free PMC article.
Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer.
Dias Costa A, Väyrynen SA, Chawla A, Zhang J, Väyrynen JP, Lau MC, Williams HL, Yuan C, Morales-Oyarvide V, Elganainy D, Singh H, Cleary JM, Perez K, Ng K, Freed-Pastor W, Mancias JD, Dougan SK, Wang J, Rubinson DA, Dunne RF, Kozak MM, Brais L, Reilly E, Clancy T, Linehan DC, Chang DT, Hezel AF, Koong AC, Aguirre AJ, Wolpin BM, Nowak JA. Dias Costa A, et al. Clin Cancer Res. 2022 Dec 1;28(23):5167-5179. doi: 10.1158/1078-0432.CCR-22-1125. Clin Cancer Res. 2022. PMID: 36129461 Free PMC article.
Emerging Role of Targeted Therapy in Metastatic Pancreatic Adenocarcinoma.
Huffman BM, Ellis H, Jordan AC, Freed-Pastor WA, Perez K, Rubinson DA, Sethi N, Singh H, Surana R, Wolpin BM, Aguirre AJ, Cleary JM. Huffman BM, et al. Cancers (Basel). 2022 Dec 16;14(24):6223. doi: 10.3390/cancers14246223. Cancers (Basel). 2022. PMID: 36551707 Free PMC article. Review.