IK6 BX004603/BX/BLRD VA/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	1
2018	6
2019	8
2020	5
2021	10
2022	9
2023	7
2024	4

1

Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells.

Haque TT, Taruselli MT, Kee SA, Dailey JM, Pondicherry N, Gajewski-Kurdziel PA, Zellner MP, Stephenson DJ, MacKnight HP, Straus DB, Kankaria R, Jackson KG, Chumanevich AP, Fukuoka Y, Schwartz LB, Blakely RD, Oskeritzian CA, Chalfant CE, Martin RK, Ryan JJ. Haque TT, et al. Sci Signal. 2023 Sep 12;16(802):eabc9089. doi: 10.1126/scisignal.abc9089. Epub 2023 Sep 12. Sci Signal. 2023. PMID: 37699080 Free PMC article.

2

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.

Ung J, Tan SF, Fox TE, Shaw JJP, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP Jr, Feith DJ. Ung J, et al. Cancers (Basel). 2023 Dec 15;15(24):5866. doi: 10.3390/cancers15245866. Cancers (Basel). 2023. PMID: 38136410 Free PMC article.

3

Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function.

Vu NT, Kim M, Stephenson DJ, MacKnight HP, Chalfant CE. Vu NT, et al. Mol Cancer Res. 2022 Sep 2;20(9):1429-1442. doi: 10.1158/1541-7786.MCR-22-0085. Mol Cancer Res. 2022. PMID: 35560154 Free PMC article.

4

Evidence for Systemic Reactive Oxygen Species in UVB-mediated Microvesicle Formation.

McGlone CL, Christian L, Schmeusser B, Liu L, Chalfant CE, Stephensen DJ, Sherwin CM, Rapp CM, Sattouf Z, Rohan CA, Morris C, Chen Y, Travers JB. McGlone CL, et al. Photochem Photobiol. 2022 Jan;98(1):242-247. doi: 10.1111/php.13494. Epub 2021 Aug 7. Photochem Photobiol. 2022. PMID: 34324712 Free PMC article.

5

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia.

Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC. Fisher-Wellman KH, et al. Cancers (Basel). 2023 Mar 21;15(6):1883. doi: 10.3390/cancers15061883. Cancers (Basel). 2023. PMID: 36980769 Free PMC article.

6

Functional inhibition or genetic deletion of acid sphingomyelinase bacteriostatically inhibits Anaplasma phagocytophilum infection in vivo.

Naimi WA, Gumpf JJ, Cockburn CL, Camus S, Chalfant CE, Li PL, Carlyon JA. Naimi WA, et al. Pathog Dis. 2021 Jan 6;79(1):ftaa072. doi: 10.1093/femspd/ftaa072. Pathog Dis. 2021. PMID: 33220685 Free PMC article.

7

Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells.

Tahia F, Basu SK, Prislovsky A, Mondal K, Ma D, Kochat H, Brown K, Stephenson DJ, Chalfant CE, Mandal N. Tahia F, et al. Exp Eye Res. 2024 May;242:109852. doi: 10.1016/j.exer.2024.109852. Epub 2024 Mar 8. Exp Eye Res. 2024. PMID: 38460719

8

Sustained local inhibition of thrombin preserves renal microarchitecture and function after onset of acute kidney injury.

Vargas I, Stephenson DJ, Baldwin M, Gaut JP, Chalfant CE, Pan H, Wickline SA. Vargas I, et al. Nanomedicine. 2021 Nov;38:102449. doi: 10.1016/j.nano.2021.102449. Epub 2021 Jul 23. Nanomedicine. 2021. PMID: 34303838 Free PMC article.

9

Inhibition of Epidermal Growth Factor Receptor Signaling by Antisense Oligonucleotides as a Novel Approach to Epidermal Growth Factor Receptor Inhibition.

Madanayake TW, Welsh EA, Darville LNF, Koomen JM, Chalfant CE, Haura EB, Robinson TJ. Madanayake TW, et al. Nucleic Acid Ther. 2022 Oct;32(5):391-400. doi: 10.1089/nat.2021.0101. Epub 2022 Jul 20. Nucleic Acid Ther. 2022. PMID: 35861718 Free PMC article.

10

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A₂α.

Hirano Y, Gao YG, Stephenson DJ, Vu NT, Malinina L, Simanshu DK, Chalfant CE, Patel DJ, Brown RE. Hirano Y, et al. Elife. 2021 Nov 29;10:e75278. doi: 10.7554/eLife.75278. Elife. 2021. PMID: 34843431 Free PMC article.

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