HHSN272201400051C/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	4
2018	4
2019	1
2020	1
2021	3
2022	1
2024	0

1

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.

Moroishi T, Hayashi T, Pan WW, Fujita Y, Holt MV, Qin J, Carson DA, Guan KL. Moroishi T, et al. Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005. Cell. 2016. PMID: 27912060 Free PMC article.

2

Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators.

Shukla NM, Chan M, Hayashi T, Carson DA, Cottam HB. Shukla NM, et al. ACS Med Chem Lett. 2018 Dec 3;9(12):1156-1159. doi: 10.1021/acsmedchemlett.8b00566. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613317 Free PMC article.

3

Mitochondria-dependent synthetic small-molecule vaccine adjuvants for influenza virus infection.

Sato-Kaneko F, Yao S, Lao FS, Nan J, Shpigelman J, Cheng A, Saito T, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Molina AJ, Corr M, Hayashi T, Carson DA. Sato-Kaneko F, et al. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2025718118. doi: 10.1073/pnas.2025718118. Proc Natl Acad Sci U S A. 2021. PMID: 34078669 Free PMC article.

4

Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity.

Saito T, Shukla NM, Sato-Kaneko F, Sako Y, Hosoya T, Yao S, Lao FS, Messer K, Pu M, Chan M, Chu PJ, Cottam HB, Hayashi T, Carson DA, Corr M. Saito T, et al. ACS Chem Biol. 2022 Jan 21;17(1):217-229. doi: 10.1021/acschembio.1c00883. Epub 2022 Jan 5. ACS Chem Biol. 2022. PMID: 34985883 Free PMC article.

5

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, Hayashi T, Cohen EE. Sato-Kaneko F, et al. JCI Insight. 2017 Sep 21;2(18):e93397. doi: 10.1172/jci.insight.93397. eCollection 2017 Sep 21. JCI Insight. 2017. PMID: 28931759 Free PMC article.

6

A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity.

Sato-Kaneko F, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Chu PJ, Burkhart D, Schoener R, Matsutani T, Carson DA, Corr M, Hayashi T. Sato-Kaneko F, et al. Front Immunol. 2020 Jun 19;11:1207. doi: 10.3389/fimmu.2020.01207. eCollection 2020. Front Immunol. 2020. PMID: 32636840 Free PMC article.

7

Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation.

Shukla NM, Chan M, Lao FS, Chu PJ, Belsuzarri M, Yao S, Nan J, Sato-Kaneko F, Saito T, Hayashi T, Corr M, Carson DA, Cottam HB. Shukla NM, et al. Bioorg Med Chem. 2021 Aug 1;43:116242. doi: 10.1016/j.bmc.2021.116242. Epub 2021 May 30. Bioorg Med Chem. 2021. PMID: 34274759 Free PMC article.

8

Structure-Activity Relationship Studies To Identify Affinity Probes in Bis-aryl Sulfonamides That Prolong Immune Stimuli.

Chan M, Lao FS, Chu PJ, Shpigelman J, Yao S, Nan J, Sato-Kaneko F, Li V, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. Chan M, et al. J Med Chem. 2019 Nov 14;62(21):9521-9540. doi: 10.1021/acs.jmedchem.9b00870. Epub 2019 Oct 25. J Med Chem. 2019. PMID: 31603681 Free PMC article.

9

Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.

Saito T, Sako Y, Sato-Kaneko F, Hosoya T, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Chan M, Chu PJ, Cottam HB, Hayashi T, Carson DA, Corr M. Saito T, et al. Front Immunol. 2021 Sep 28;12:701445. doi: 10.3389/fimmu.2021.701445. eCollection 2021. Front Immunol. 2021. PMID: 34650551 Free PMC article.

10

Identification of Biologically Active Pyrimido[5,4-b]indoles That Prolong NF-κB Activation without Intrinsic Activity.

Chan M, Ahmadi A, Yao S, Sato-Kaneko F, Messer K, Pu M, Nguyen B, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. Chan M, et al. ACS Comb Sci. 2017 Aug 14;19(8):533-543. doi: 10.1021/acscombsci.7b00080. Epub 2017 Jul 13. ACS Comb Sci. 2017. PMID: 28657707 Free PMC article.

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