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The ATR inhibitor elimusertib exhibits anti-lymphoma activity and synergizes with the PI3K inhibitor copanlisib.
Br J Haematol. 2024 Jan;204(1):191-205. doi: 10.1111/bjh.19218. Epub 2023 Nov 27.
Br J Haematol. 2024.
PMID: 38011941
ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma.
Sartori G, Napoli S, Cascione L, Chung EYL, Priebe V, Arribas AJ, Mensah AA, Dall'Angelo M, Falzarano C, Barnabei L, Forcato M, Rinaldi A, Bicciato S, Thome M, Bertoni F.
Sartori G, et al.
J Exp Clin Cancer Res. 2021 Nov 11;40(1):357. doi: 10.1186/s13046-021-02159-3.
J Exp Clin Cancer Res. 2021.
PMID: 34763718
Free PMC article.
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ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells.
Chung EYL, Sartori G, Ponzoni M, Cascione L, Priebe V, Xu-Monette ZY, Fang X, Zhang M, Visco C, Tzankov A, Rinaldi A, Sgrignani J, Zucca E, Rossi D, Cavalli A, Inghirami G, Scott DW, Young KH, Bertoni F.
Chung EYL, et al.
Br J Haematol. 2023 Oct;203(2):244-254. doi: 10.1111/bjh.19018. Epub 2023 Aug 16.
Br J Haematol. 2023.
PMID: 37584198
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