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Page 1
Selective inhibition of BET bromodomains.
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. Filippakopoulos P, et al. Nature. 2010 Dec 23;468(7327):1067-73. doi: 10.1038/nature09504. Epub 2010 Sep 24. Nature. 2010. PMID: 20871596 Free PMC article.
T-ARG-eting E2F-1 growth control.
Moehlenbrink J, La Thangue NB. Moehlenbrink J, et al. Cell Cycle. 2012 Aug 15;11(16):2973-4. doi: 10.4161/cc.21467. Epub 2012 Aug 8. Cell Cycle. 2012. PMID: 22871730 Free PMC article.
Regulation of actin nucleation and autophagosome formation.
Coutts AS, La Thangue NB. Coutts AS, et al. Cell Mol Life Sci. 2016 Sep;73(17):3249-63. doi: 10.1007/s00018-016-2224-z. Epub 2016 May 4. Cell Mol Life Sci. 2016. PMID: 27147468 Free PMC article. Review.
HDAC Inhibitors.
Olzscha H, Bekheet ME, Sheikh S, La Thangue NB. Olzscha H, et al. Methods Mol Biol. 2016;1436:281-303. doi: 10.1007/978-1-4939-3667-0_19. Methods Mol Biol. 2016. PMID: 27246222
Lysine methylation and the regulation of p53.
Carr SM, Munro S, La Thangue NB. Carr SM, et al. Essays Biochem. 2012;52:79-92. doi: 10.1042/bse0520079. Essays Biochem. 2012. PMID: 22708565 Review.
To live or let die - complexity within the E2F1 pathway.
Poppy Roworth A, Ghari F, La Thangue NB. Poppy Roworth A, et al. Mol Cell Oncol. 2015 Jan 30;2(1):e970480. doi: 10.4161/23723548.2014.970480. eCollection 2015 Jan-Mar. Mol Cell Oncol. 2015. PMID: 27308406 Free PMC article. Review.
39 results