F32 GM020501/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	1
2006	1
2008	2
2009	7
2010	5
2011	12
2012	7
2013	2
2015	3
2016	4
2017	2
2018	5
2019	2
2020	1
2021	1
2022	1
2024	1

1

Review of four major distinct types of human phospholipase A₂.

Vasquez AM, Mouchlis VD, Dennis EA. Vasquez AM, et al. Adv Biol Regul. 2018 Jan;67:212-218. doi: 10.1016/j.jbior.2017.10.009. Epub 2017 Oct 23. Adv Biol Regul. 2018. PMID: 29248300 Free PMC article. Review.

2

Phospholipase A₂ catalysis and lipid mediator lipidomics.

Mouchlis VD, Dennis EA. Mouchlis VD, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun;1864(6):766-771. doi: 10.1016/j.bbalip.2018.08.010. Epub 2018 Aug 23. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30905345 Free PMC article. Review.

3

New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2.

Magrioti V, Nikolaou A, Smyrniotou A, Shah I, Constantinou-Kokotou V, Dennis EA, Kokotos G. Magrioti V, et al. Bioorg Med Chem. 2013 Sep 15;21(18):5823-9. doi: 10.1016/j.bmc.2013.07.010. Epub 2013 Jul 16. Bioorg Med Chem. 2013. PMID: 23916152 Free PMC article.

4

Substrate-Specific Inhibition Constants for Phospholipase A₂ Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics.

Mouchlis VD, Armando A, Dennis EA. Mouchlis VD, et al. J Med Chem. 2019 Feb 28;62(4):1999-2007. doi: 10.1021/acs.jmedchem.8b01568. Epub 2019 Feb 4. J Med Chem. 2019. PMID: 30615445 Free PMC article.

5

Structural basis for differential neutralization of ebolaviruses.

Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL Jr, Chandran K, Dye JM, Saphire EO. Bale S, et al. Viruses. 2012 Apr;4(4):447-70. doi: 10.3390/v4040447. Epub 2012 Apr 5. Viruses. 2012. PMID: 22590681 Free PMC article. Review.

6

Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A₂ (GIVA cPLA₂).

Psarra A, Kokotou MG, Galiatsatou G, Mouchlis VD, Dennis EA, Kokotos G. Psarra A, et al. ACS Omega. 2018 Aug 31;3(8):8843-8853. doi: 10.1021/acsomega.8b01214. Epub 2018 Aug 9. ACS Omega. 2018. PMID: 30197994 Free PMC article.

7

Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A₂ inhibitors.

Mouchlis VD, Mu C, Hammons R, Dennis EA. Mouchlis VD, et al. Adv Biol Regul. 2020 May;76:100719. doi: 10.1016/j.jbior.2020.100719. Epub 2020 Mar 10. Adv Biol Regul. 2020. PMID: 32199750 Free PMC article.

8

Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates.

Mouchlis VD, Bucher D, McCammon JA, Dennis EA. Mouchlis VD, et al. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):E516-25. doi: 10.1073/pnas.1424651112. Epub 2015 Jan 26. Proc Natl Acad Sci U S A. 2015. PMID: 25624474 Free PMC article.

9

Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity.

Mouchlis VD, Chen Y, McCammon JA, Dennis EA. Mouchlis VD, et al. J Am Chem Soc. 2018 Mar 7;140(9):3285-3291. doi: 10.1021/jacs.7b12045. Epub 2018 Feb 26. J Am Chem Soc. 2018. PMID: 29342349 Free PMC article.

10

2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A₂.

Kokotou MG, Galiatsatou G, Magrioti V, Koutoulogenis G, Barbayianni E, Limnios D, Mouchlis VD, Satpathy B, Navratil A, Dennis EA, Kokotos G. Kokotou MG, et al. Sci Rep. 2017 Aug 1;7(1):7025. doi: 10.1038/s41598-017-07330-5. Sci Rep. 2017. PMID: 28765606 Free PMC article.

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