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KRAS is vulnerable to reversible switch-II pocket engagement in cells.
Vasta JD, Peacock DM, Zheng Q, Walker JA, Zhang Z, Zimprich CA, Thomas MR, Beck MT, Binkowski BF, Corona CR, Robers MB, Shokat KM. Vasta JD, et al. Nat Chem Biol. 2022 Jun;18(6):596-604. doi: 10.1038/s41589-022-00985-w. Epub 2022 Mar 21. Nat Chem Biol. 2022. PMID: 35314814 Free PMC article.