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Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice.
Green CL, Trautman ME, Chaiyakul K, Jain R, Alam YH, Babygirija R, Pak HH, Sonsalla MM, Calubag MF, Yeh CY, Bleicher A, Novak G, Liu TT, Newman S, Ricke WA, Matkowskyj KA, Ong IM, Jang C, Simcox J, Lamming DW. Green CL, et al. Cell Metab. 2023 Nov 7;35(11):1976-1995.e6. doi: 10.1016/j.cmet.2023.10.005. Cell Metab. 2023. PMID: 37939658 Free PMC article.
Resistance exercise protects mice from protein-induced fat accretion.
Trautman ME, Braucher LN, Elliehausen C, Zhu WG, Zelenovskiy E, Green M, Sonsalla MM, Yeh CY, Hornberger TA, Konopka AR, Lamming DW. Trautman ME, et al. Elife. 2023 Nov 29;12:RP91007. doi: 10.7554/eLife.91007. Elife. 2023. PMID: 38019262 Free PMC article.
Protein restriction slows the development and progression of Alzheimer's disease in mice.
Babygirija R, Sonsalla MM, Mill J, James I, Han JH, Green CL, Calubag MF, Wade G, Tobon A, Michael J, Trautman MM, Matoska R, Yeh CY, Grunow I, Pak HH, Rigby MJ, Baldwin DA, Niemi NM, Denu JM, Puglielli L, Simcox J, Lamming DW. Babygirija R, et al. Res Sq [Preprint]. 2024 Apr 24:rs.3.rs-3342413. doi: 10.21203/rs.3.rs-3342413/v2. Res Sq. 2024. Update in: Nat Commun. 2024 Jun 18;15(1):5217. doi: 10.1038/s41467-024-49589-z PMID: 37790423 Free PMC article. Updated. Preprint.
Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease.
Babygirija R, Sonsalla MM, Mill J, James I, Han JH, Green CL, Calubag MF, Wade G, Tobon A, Michael J, Trautman MM, Matoska R, Yeh CY, Grunow I, Pak HH, Rigby MJ, Baldwin DA, Niemi NM, Denu JM, Puglielli L, Simcox J, Lamming DW. Babygirija R, et al. Nat Commun. 2024 Jun 18;15(1):5217. doi: 10.1038/s41467-024-49589-z. Nat Commun. 2024. PMID: 38890307 Free PMC article.
The Fourth Annual Symposium of the Midwest Aging Consortium.
Kim J, Buffenstein R, Bronikowski AM, Pilar Vanegas ND, Rosas L, Agudelo-Garcia P, Mora AL, Rojas M, Englund DA, LeBrasseur NK, Nunes A, Robbins PD, Kohut ML, Kothadiya S, Bardhan R, Camell CD, Sturmlechner I, Goronzy JJ, Yeh CY, Lamming DW, Huang S, Leiser SF, Escorcia W, Gill MS, Taylor JR, Helfand SL, Korm S, Gribble KE, Pehar M, Blaszkiewicz M, Townsend KL, McGregor ER, Anderson RM, Stilgenbauer L, Sadagurski M, Taylor A, McNeill E, Stoeger T, Bai H. Kim J, et al. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae236. doi: 10.1093/gerona/glae236. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39498863 Free PMC article.
Dietary isoleucine content defines the metabolic and molecular response to a Western diet.
Trautman ME, Green CL, MacArthur MR, Chaiyakul K, Alam YH, Yeh CY, Babygirija R, James I, Gilpin M, Zelenovskiy E, Green M, Marshall RN, Sonsalla MM, Flores V, Simcox JA, Ong IM, Malecki KC, Jang C, Lamming DW. Trautman ME, et al. bioRxiv [Preprint]. 2024 Jun 3:2024.05.30.596340. doi: 10.1101/2024.05.30.596340. bioRxiv. 2024. PMID: 38895446 Free PMC article. Preprint.
Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer's disease.
Sonsalla MM, Babygirija R, Johnson M, Cai S, Cole M, Yeh CY, Grunow I, Liu Y, Vertein D, Calubag MF, Trautman ME, Green CL, Rigby MJ, Puglielli L, Lamming DW. Sonsalla MM, et al. bioRxiv [Preprint]. 2024 Jul 2:2024.06.27.600472. doi: 10.1101/2024.06.27.600472. bioRxiv. 2024. Update in: Geroscience. 2024 Sep 14. doi: 10.1007/s11357-024-01337-3 PMID: 39005334 Free PMC article. Updated. Preprint.