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CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CP, Bose R, Travaglini KJ, Lam VL, Goodness D, Dixon G, Marzette E, Jin J, Tian R, Tse E, Abskharon R, Pan H, Carroll EC, Lawrence RE, Gestwicki JE, Eisenberg D, Kanaan NM, Southworth DR, Gross JD, Gan L, Swaney DL, Kampmann M. Samelson AJ, et al. bioRxiv [Preprint]. 2024 Nov 4:2023.06.16.545386. doi: 10.1101/2023.06.16.545386. bioRxiv. 2024. PMID: 37398204 Free PMC article. Preprint.
Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry.
Wu T, Yu JC, Suresh A, Gale-Day ZJ, Alteen MG, Woo AS, Millbern Z, Johnson OT, Carroll EC, Partch CL, Fourches D, Vinueza NR, Vocadlo DJ, Gestwicki JE. Wu T, et al. bioRxiv [Preprint]. 2023 Jan 28:2023.01.23.525251. doi: 10.1101/2023.01.23.525251. bioRxiv. 2023. Update in: Nat Biotechnol. 2024 May 14. doi: 10.1038/s41587-024-02158-7. PMID: 36747624 Free PMC article. Updated. Preprint.