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cAMP and voltage modulate rat auditory mechanotransduction by decreasing the stiffness of gating springs.
Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2107567119. doi: 10.1073/pnas.2107567119. Epub 2022 Jul 19.
Proc Natl Acad Sci U S A. 2022.
PMID: 35858439
Free PMC article.
Decades-old model of slow adaptation in sensory hair cells is not supported in mammals.
Caprara GA, Mecca AA, Peng AW.
Caprara GA, et al.
Sci Adv. 2020 Aug 14;6(33):eabb4922. doi: 10.1126/sciadv.abb4922. eCollection 2020 Aug.
Sci Adv. 2020.
PMID: 32851178
Free PMC article.
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Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex.
Li S, Mecca A, Kim J, Caprara GA, Wagner EL, Du TT, Petrov L, Xu W, Cui R, Rebustini IT, Kachar B, Peng AW, Shin JB.
Li S, et al.
Nat Commun. 2020 Apr 29;11(1):2066. doi: 10.1038/s41467-020-15936-z.
Nat Commun. 2020.
PMID: 32350269
Free PMC article.
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