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Mechanisms and consequences of endothelial cell senescence.
Bloom SI, Islam MT, Lesniewski LA, Donato AJ. Bloom SI, et al. Nat Rev Cardiol. 2023 Jan;20(1):38-51. doi: 10.1038/s41569-022-00739-0. Epub 2022 Jul 19. Nat Rev Cardiol. 2023. PMID: 35853997 Free PMC article. Review.
Reduction of double-strand DNA break repair exacerbates vascular aging.
Bloom SI, Tucker JR, Machin DR, Abdeahad H, Adeyemo AO, Thomas TG, Bramwell RC, Lesniewski LA, Donato AJ. Bloom SI, et al. Aging (Albany NY). 2023 Oct 2;15(19):9913-9947. doi: 10.18632/aging.205066. Epub 2023 Oct 2. Aging (Albany NY). 2023. PMID: 37787989 Free PMC article.
Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice.
Islam MT, Cai J, Allen S, Moreno DG, Bloom SI, Bramwell RC, Mitton J, Horn AG, Zhu W, Donato AJ, Holland WL, Lesniewski LA. Islam MT, et al. Arterioscler Thromb Vasc Biol. 2024 May;44(5):1101-1113. doi: 10.1161/ATVBAHA.123.319375. Epub 2024 Mar 28. Arterioscler Thromb Vasc Biol. 2024. PMID: 38545783