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Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, van Rooijen N, García-Sastre A, Stanley ER, Ginhoux F, Frenette PS, Merad M. Hashimoto D, et al. Immunity. 2013 Apr 18;38(4):792-804. doi: 10.1016/j.immuni.2013.04.004. Immunity. 2013. PMID: 23601688 Free PMC article.
Adrenergic nerves govern circadian leukocyte recruitment to tissues.
Scheiermann C, Kunisaki Y, Lucas D, Chow A, Jang JE, Zhang D, Hashimoto D, Merad M, Frenette PS. Scheiermann C, et al. Immunity. 2012 Aug 24;37(2):290-301. doi: 10.1016/j.immuni.2012.05.021. Epub 2012 Aug 2. Immunity. 2012. PMID: 22863835 Free PMC article.
Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity.
Gautier EL, Chow A, Spanbroek R, Marcelin G, Greter M, Jakubzick C, Bogunovic M, Leboeuf M, van Rooijen N, Habenicht AJ, Merad M, Randolph GJ. Gautier EL, et al. J Immunol. 2012 Sep 1;189(5):2614-24. doi: 10.4049/jimmunol.1200495. Epub 2012 Aug 1. J Immunol. 2012. PMID: 22855714 Free PMC article.