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Evidence that nuclear factor-kappa B activation is critical in oxidant-induced disruption of the microtubule cytoskeleton and barrier integrity and that its inactivation is essential in epidermal growth factor-mediated protection of the monolayers of intestinal epithelia.
Banan A, Farhadi A, Fields JZ, Mutlu E, Zhang L, Keshavarzian A. Banan A, et al. J Pharmacol Exp Ther. 2003 Jul;306(1):13-28. doi: 10.1124/jpet.103.047415. J Pharmacol Exp Ther. 2003. PMID: 12815011
Inhibition of oxidant-induced nuclear factor-kappaB activation and inhibitory-kappaBalpha degradation and instability of F-actin cytoskeletal dynamics and barrier function by epidermal growth factor: key role of phospholipase-gamma isoform.
Banan A, Zhang LJ, Shaikh M, Fields JZ, Farhadi A, Keshavarzian A. Banan A, et al. J Pharmacol Exp Ther. 2004 Apr;309(1):356-68. doi: 10.1124/jpet.103.062232. Epub 2004 Jan 14. J Pharmacol Exp Ther. 2004. PMID: 14724221