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Oral transforming growth factor-beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity.
Choi SH, Myers JT, Tomchuck SL, Bonner M, Eid S, Kingsley DT, VanHeyst KA, Kim SJ, Kim BG, Huang AY. Choi SH, et al. Cancer Commun (Lond). 2024 Aug;44(8):884-888. doi: 10.1002/cac2.12589. Epub 2024 Jul 6. Cancer Commun (Lond). 2024. PMID: 38970391 Free PMC article. No abstract available.
MERTK Is a Potential Therapeutic Target in Ewing Sarcoma.
Smart SK, Yeung TY, Santos MO, McSwain LF, Wang X, Frye SV, Earp HS 3rd, DeRyckere D, Graham DK. Smart SK, et al. Cancers (Basel). 2024 Aug 12;16(16):2831. doi: 10.3390/cancers16162831. Cancers (Basel). 2024. PMID: 39199601 Free PMC article.
Systems Biology Approach Identifies Prognostic Signatures of Poor Overall Survival and Guides the Prioritization of Novel BET-CHK1 Combination Therapy for Osteosarcoma.
Pandya PH, Cheng L, Saadatzadeh MR, Bijangi-Vishehsaraei K, Tang S, Sinn AL, Trowbridge MA, Coy KL, Bailey BJ, Young CN, Ding J, Dobrota EA, Dyer S, Elmi A, Thompson Q, Barghi F, Shultz J, Albright EA, Shannon HE, Murray ME, Marshall MS, Ferguson MJ, Bertrand TE, Wurtz LD, Batra S, Li L, Renbarger JL, Pollok KE. Pandya PH, et al. Cancers (Basel). 2020 Aug 26;12(9):2426. doi: 10.3390/cancers12092426. Cancers (Basel). 2020. PMID: 32859084 Free PMC article.