CA88310/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2001	1
2002	1
2003	3
2004	3
2005	2
2024	0

1

The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4.

Seenisamy J, Rezler EM, Powell TJ, Tye D, Gokhale V, Joshi CS, Siddiqui-Jain A, Hurley LH. Seenisamy J, et al. J Am Chem Soc. 2004 Jul 21;126(28):8702-9. doi: 10.1021/ja040022b. J Am Chem Soc. 2004. PMID: 15250722

2

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.

Kim MY, Vankayalapati H, Shin-Ya K, Wierzba K, Hurley LH. Kim MY, et al. J Am Chem Soc. 2002 Mar 13;124(10):2098-9. doi: 10.1021/ja017308q. J Am Chem Soc. 2002. PMID: 11878947

3

Targeting aurora2 kinase in oncogenesis: a structural bioinformatics approach to target validation and rational drug design.

Vankayalapati H, Bearss DJ, Saldanha JW, Muñoz RM, Rojanala S, Von Hoff DD, Mahadevan D. Vankayalapati H, et al. Mol Cancer Ther. 2003 Mar;2(3):283-94. Mol Cancer Ther. 2003. PMID: 12657723

4

Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.

Kim MY, Na Y, Vankayalapati H, Gleason-Guzman M, Hurley LH. Kim MY, et al. J Med Chem. 2003 Jul 3;46(14):2958-72. doi: 10.1021/jm030096i. J Med Chem. 2003. PMID: 12825936

5

Binding of G-quadruplex-interactive agents to distinct G-quadruplexes induces different biological effects in MiaPaCa cells.

Liu W, Sun D, Hurley LH. Liu W, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1801-15. doi: 10.1080/15257770500267238. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438049

6

Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue.

Grand CL, Powell TJ, Nagle RB, Bearss DJ, Tye D, Gleason-Guzman M, Hurley LH. Grand CL, et al. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6140-5. doi: 10.1073/pnas.0400460101. Epub 2004 Apr 12. Proc Natl Acad Sci U S A. 2004. Retraction in: Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):516. doi: 10.1073/pnas.0408999101 PMID: 15079086 Free PMC article. Retracted.

7

Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biological effects.

Duan W, Rangan A, Vankayalapati H, Kim MY, Zeng Q, Sun D, Han H, Fedoroff OY, Nishioka D, Rha SY, Izbicka E, Von Hoff DD, Hurley LH. Duan W, et al. Mol Cancer Ther. 2001 Dec;1(2):103-20. Mol Cancer Ther. 2001. PMID: 12467228

8

Design, synthesis, and biological evaluation of a series of fluoroquinoanthroxazines with contrasting dual mechanisms of action against topoisomerase II and G-quadruplexes.

Kim MY, Duan W, Gleason-Guzman M, Hurley LH. Kim MY, et al. J Med Chem. 2003 Feb 13;46(4):571-83. doi: 10.1021/jm0203377. J Med Chem. 2003. PMID: 12570378

9

The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer.

Rojanala S, Han H, Muñoz RM, Browne W, Nagle R, Von Hoff DD, Bearss DJ. Rojanala S, et al. Mol Cancer Ther. 2004 Apr;3(4):451-7. Mol Cancer Ther. 2004. PMID: 15078988

10

Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure.

Seenisamy J, Bashyam S, Gokhale V, Vankayalapati H, Sun D, Siddiqui-Jain A, Streiner N, Shin-Ya K, White E, Wilson WD, Hurley LH. Seenisamy J, et al. J Am Chem Soc. 2005 Mar 9;127(9):2944-59. doi: 10.1021/ja0444482. J Am Chem Soc. 2005. PMID: 15740131

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