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Page 1
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.
Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, Lu G, Zhang L, Zhang C, Zhang J, Sun Y, Qi T, Lyu Y, Ren ZZ, Tan XM, Yin J, Lan F, Liu Y, Yang H, Qian M, Duan C, Chang X, Zhou Y, Shen L, Baldwin AS, Guan KL, Xiong Y, Ye D. Chen LL, et al. Nat Cell Biol. 2022 Mar;24(3):353-363. doi: 10.1038/s41556-022-00853-8. Epub 2022 Mar 7. Nat Cell Biol. 2022. PMID: 35256775 Free PMC article.
Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.
Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, Li B, Luo W, Zhang X, Chen X, Mendell JT, Xu L, Kapur P, Baldwin AS, Brugarolas J, Zhang Q. Hu L, et al. Mol Cell. 2024 Feb 15;84(4):776-790.e5. doi: 10.1016/j.molcel.2023.12.010. Epub 2024 Jan 10. Mol Cell. 2024. PMID: 38211588
Alterations of metabolic genes and metabolites in cancer.
Oermann EK, Wu J, Guan KL, Xiong Y. Oermann EK, et al. Semin Cell Dev Biol. 2012 Jun;23(4):370-80. doi: 10.1016/j.semcdb.2012.01.013. Epub 2012 Jan 28. Semin Cell Dev Biol. 2012. PMID: 22306135 Free PMC article. Review.
Tumour metabolites hinder DNA repair.
Chen LL, Xiong Y. Chen LL, et al. Nature. 2020 Jun;582(7813):492-494. doi: 10.1038/d41586-020-01569-1. Nature. 2020. PMID: 32572248 Free PMC article. No abstract available.
34 results