C309/A11566/Cancer Research UK/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2012	1
2014	2
2015	6
2016	6
2017	1
2024	0

1

Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapy.

Myers SM, Collins I. Myers SM, et al. Future Med Chem. 2016;8(4):463-89. doi: 10.4155/fmc.16.5. Epub 2016 Mar 15. Future Med Chem. 2016. PMID: 26976726 Free PMC article. Review.

2

Distinctive Behaviors of Druggable Proteins in Cellular Networks.

Mitsopoulos C, Schierz AC, Workman P, Al-Lazikani B. Mitsopoulos C, et al. PLoS Comput Biol. 2015 Dec 23;11(12):e1004597. doi: 10.1371/journal.pcbi.1004597. eCollection 2015 Dec. PLoS Comput Biol. 2015. PMID: 26699810 Free PMC article.

3

Tissue-based approaches to study pharmacodynamic endpoints in early phase oncology clinical trials.

Ang JE, Kaye S, Banerji U. Ang JE, et al. Curr Drug Targets. 2012 Nov;13(12):1525-34. doi: 10.2174/138945012803530062. Curr Drug Targets. 2012. PMID: 22974395 Free PMC article. Review.

4

Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines.

Patel A, Sharp SY, Hall K, Lewis W, Stevens MF, Workman P, Moody CJ. Patel A, et al. Org Biomol Chem. 2016 Apr 28;14(16):3889-905. doi: 10.1039/c6ob00471g. Epub 2016 Apr 1. Org Biomol Chem. 2016. PMID: 27035072

5

Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.

Gurden MD, Westwood IM, Faisal A, Naud S, Cheung KM, McAndrew C, Wood A, Schmitt J, Boxall K, Mak G, Workman P, Burke R, Hoelder S, Blagg J, Van Montfort RL, Linardopoulos S. Gurden MD, et al. Cancer Res. 2015 Aug 15;75(16):3340-54. doi: 10.1158/0008-5472.CAN-14-3272. Epub 2015 Jul 22. Cancer Res. 2015. PMID: 26202014

6

Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.

Tisi D, Chiarparin E, Tamanini E, Pathuri P, Coyle JE, Hold A, Holding FP, Amin N, Martin AC, Rich SJ, Berdini V, Yon J, Acklam P, Burke R, Drouin L, Harmer JE, Jeganathan F, van Montfort RL, Newbatt Y, Tortorici M, Westlake M, Wood A, Hoelder S, Heightman TD. Tisi D, et al. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105. doi: 10.1021/acschembio.6b00308. Epub 2016 Sep 27. ACS Chem Biol. 2016. PMID: 27571355

7

Insights into significance of combined inhibition of MEK and m-TOR signalling output in KRAS mutant non-small-cell lung cancer.

Broutin S, Stewart A, Thavasu P, Paci A, Bidart JM, Banerji U. Broutin S, et al. Br J Cancer. 2016 Aug 23;115(5):549-52. doi: 10.1038/bjc.2016.220. Epub 2016 Jul 21. Br J Cancer. 2016. PMID: 27441499 Free PMC article.

8

Hyperglycemia and Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin (PI3K/AKT/mTOR) Inhibitors in Phase I Trials: Incidence, Predictive Factors, and Management.

Khan KH, Wong M, Rihawi K, Bodla S, Morganstein D, Banerji U, Molife LR. Khan KH, et al. Oncologist. 2016 Jul;21(7):855-60. doi: 10.1634/theoncologist.2015-0248. Epub 2016 May 5. Oncologist. 2016. PMID: 27151652 Free PMC article. Clinical Trial.

9

A model β-sheet interaction and thermodynamic analysis of β-strand mimetics.

Robinson CW, Rye CS, Chessum NE, Jones K. Robinson CW, et al. Org Biomol Chem. 2015 Jul 21;13(27):7402-7. doi: 10.1039/c5ob00886g. Org Biomol Chem. 2015. PMID: 26088610

10

Increasing the coverage of medicinal chemistry-relevant space in commercial fragments screening.

Mok NY, Brenk R, Brown N. Mok NY, et al. J Chem Inf Model. 2014 Jan 27;54(1):79-85. doi: 10.1021/ci400632y. Epub 2014 Jan 9. J Chem Inf Model. 2014. PMID: 24405118 Free PMC article.

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