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Page 1
Epigenetics in myelodysplastic syndromes.
Heuser M, Yun H, Thol F. Heuser M, et al. Semin Cancer Biol. 2018 Aug;51:170-179. doi: 10.1016/j.semcancer.2017.07.009. Epub 2017 Aug 2. Semin Cancer Biol. 2018. PMID: 28778402 Free PMC article. Review.
Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis.
Thol F, Klesse S, Köhler L, Gabdoulline R, Kloos A, Liebich A, Wichmann M, Chaturvedi A, Fabisch J, Gaidzik VI, Paschka P, Bullinger L, Bug G, Serve H, Göhring G, Schlegelberger B, Lübbert M, Kirchner H, Wattad M, Kraemer D, Hertenstein B, Heil G, Fiedler W, Krauter J, Schlenk RF, Döhner K, Döhner H, Ganser A, Heuser M. Thol F, et al. Leukemia. 2017 Jun;31(6):1286-1295. doi: 10.1038/leu.2016.345. Epub 2016 Nov 24. Leukemia. 2017. PMID: 27881874 Free PMC article.
Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.
Chaturvedi A, Herbst L, Pusch S, Klett L, Goparaju R, Stichel D, Kaulfuss S, Panknin O, Zimmermann K, Toschi L, Neuhaus R, Haegebarth A, Rehwinkel H, Hess-Stumpp H, Bauser M, Bochtler T, Struys EA, Sharma A, Bakkali A, Geffers R, Araujo-Cruz MM, Thol F, Gabdoulline R, Ganser A, Ho AD, von Deimling A, Rippe K, Heuser M, Krämer A. Chaturvedi A, et al. Leukemia. 2017 Oct;31(10):2020-2028. doi: 10.1038/leu.2017.46. Epub 2017 Jan 31. Leukemia. 2017. PMID: 28232670 Free PMC article.
Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate.
Chaturvedi A, Araujo Cruz MM, Jyotsana N, Sharma A, Goparaju R, Schwarzer A, Görlich K, Schottmann R, Struys EA, Jansen EE, Rohde C, Müller-Tidow C, Geffers R, Göhring G, Ganser A, Thol F, Heuser M. Chaturvedi A, et al. Leukemia. 2016 Aug;30(8):1708-15. doi: 10.1038/leu.2016.71. Epub 2016 Apr 11. Leukemia. 2016. PMID: 27063596 Free PMC article.
Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia.
Mohanty S, Jyotsana N, Sharma A, Kloos A, Gabdoulline R, Othman B, Lai CK, Schottmann R, Mandhania M, Schmoellerl J, Grebien F, Ramsay E, Thomas A, Vornlocher HP, Ganser A, Thol F, Heuser M. Mohanty S, et al. Cancers (Basel). 2020 Sep 26;12(10):2766. doi: 10.3390/cancers12102766. Cancers (Basel). 2020. PMID: 32993115 Free PMC article.
IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction-a retrospective propensity score analysis.
Kattih B, Shirvani A, Klement P, Garrido AM, Gabdoulline R, Liebich A, Brandes M, Chaturvedi A, Seeger T, Thol F, Göhring G, Schlegelberger B, Geffers R, John D, Bavendiek U, Bauersachs J, Ganser A, Heineke J, Heuser M. Kattih B, et al. Leukemia. 2021 May;35(5):1301-1316. doi: 10.1038/s41375-020-01043-x. Epub 2020 Sep 18. Leukemia. 2021. PMID: 32948843 Free PMC article.
Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia.
Kloos A, Mintzas K, Winckler L, Gabdoulline R, Alwie Y, Jyotsana N, Kattre N, Schottmann R, Scherr M, Gupta C, Adams FF, Schwarzer A, Heckl D, Schambach A, Imren S, Humphries RK, Ganser A, Thol F, Heuser M. Kloos A, et al. Leukemia. 2020 Nov;34(11):2951-2963. doi: 10.1038/s41375-020-0929-3. Epub 2020 Jun 24. Leukemia. 2020. PMID: 32576961 Free PMC article.
16 results