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Personalized therapeutics: HIV treatment in adolescents.
Rakhmanina NY, Capparelli EV, van den Anker JN. Rakhmanina NY, et al. Clin Pharmacol Ther. 2008 Dec;84(6):734-40. doi: 10.1038/clpt.2008.187. Epub 2008 Oct 1. Clin Pharmacol Ther. 2008. PMID: 18830226 Free PMC article. Review.
Low cerebrospinal fluid concentrations of the nucleotide HIV reverse transcriptase inhibitor, tenofovir.
Best BM, Letendre SL, Koopmans P, Rossi SS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Capparelli EV, Ellis RJ, Grant I; CHARTER Study Group. Best BM, et al. J Acquir Immune Defic Syndr. 2012 Apr 1;59(4):376-81. doi: 10.1097/QAI.0b013e318247ec54. J Acquir Immune Defic Syndr. 2012. PMID: 22217676 Free PMC article.
Infliximab treatment of intravenous immunoglobulin-resistant Kawasaki disease.
Burns JC, Best BM, Mejias A, Mahony L, Fixler DE, Jafri HS, Melish ME, Jackson MA, Asmar BI, Lang DJ, Connor JD, Capparelli EV, Keen ML, Mamun K, Keenan GF, Ramilo O. Burns JC, et al. J Pediatr. 2008 Dec;153(6):833-8. doi: 10.1016/j.jpeds.2008.06.011. Epub 2008 Jul 30. J Pediatr. 2008. PMID: 18672254 Free PMC article. Clinical Trial.
A randomized controlled trial of therapeutic drug monitoring in treatment-naive and -experienced HIV-1-infected patients.
Best BM, Goicoechea M, Witt MD, Miller L, Daar ES, Diamond C, Tilles JG, Kemper CA, Larsen R, Holland DT, Sun S, Jain S, Wagner G, Capparelli EV, McCutchan JA, Haubrich RH; California Collaborative Treatment Group 578 Study Team. Best BM, et al. J Acquir Immune Defic Syndr. 2007 Dec 1;46(4):433-42. doi: 10.1097/QAI.0b013e318156f029. J Acquir Immune Defic Syndr. 2007. PMID: 17786128 Clinical Trial.
Efavirenz concentrations in CSF exceed IC50 for wild-type HIV.
Best BM, Koopmans PP, Letendre SL, Capparelli EV, Rossi SS, Clifford DB, Collier AC, Gelman BB, Mbeo G, McCutchan JA, Simpson DM, Haubrich R, Ellis R, Grant I; CHARTER Group. Best BM, et al. J Antimicrob Chemother. 2011 Feb;66(2):354-7. doi: 10.1093/jac/dkq434. Epub 2010 Nov 23. J Antimicrob Chemother. 2011. PMID: 21098541 Free PMC article.