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The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands.
J Biol Chem. 2002 Sep 20;277(38):35105-12. doi: 10.1074/jbc.M201575200. Epub 2002 Jul 17.
J Biol Chem. 2002.
PMID: 12124379
Free article.
Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3.
Cowart LA, Falck JR, Capdevila JH.
Cowart LA, et al.
Arch Biochem Biophys. 2001 Mar 1;387(1):117-24. doi: 10.1006/abbi.2000.2246.
Arch Biochem Biophys. 2001.
PMID: 11368173
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