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Embryo model completes gastrulation to neurulation and organogenesis.
Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen DY, Aguilera-Castrejon A, Hanna JH, Elowitz MB, Hollfelder F, Shendure J, Glover DM, Zernicka-Goetz M. Amadei G, et al. Nature. 2022 Oct;610(7930):143-153. doi: 10.1038/s41586-022-05246-3. Epub 2022 Aug 25. Nature. 2022. PMID: 36007540 Free PMC article.
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications.
Shi J, Zhang Y, Tan D, Zhang X, Yan M, Zhang Y, Franklin R, Shahbazi M, Mackinlay K, Liu S, Kuhle B, James ER, Zhang L, Qu Y, Zhai Q, Zhao W, Zhao L, Zhou C, Gu W, Murn J, Guo J, Carrell DT, Wang Y, Chen X, Cairns BR, Yang XL, Schimmel P, Zernicka-Goetz M, Cheloufi S, Zhang Y, Zhou T, Chen Q. Shi J, et al. Nat Cell Biol. 2021 Apr;23(4):424-436. doi: 10.1038/s41556-021-00652-7. Epub 2021 Apr 5. Nat Cell Biol. 2021. PMID: 33820973 Free PMC article.
Stem-cell-based human and mouse embryo models.
Bao M, Cornwall-Scoones J, Zernicka-Goetz M. Bao M, et al. Curr Opin Genet Dev. 2022 Oct;76:101970. doi: 10.1016/j.gde.2022.101970. Epub 2022 Aug 18. Curr Opin Genet Dev. 2022. PMID: 35988317 Free PMC article. Review.
Human embryo polarization requires PLC signaling to mediate trophectoderm specification.
Zhu M, Shahbazi M, Martin A, Zhang C, Sozen B, Borsos M, Mandelbaum RS, Paulson RJ, Mole MA, Esbert M, Titus S, Scott RT, Campbell A, Fishel S, Gradinaru V, Zhao H, Wu K, Chen ZJ, Seli E, de Los Santos MJ, Zernicka Goetz M. Zhu M, et al. Elife. 2021 Sep 27;10:e65068. doi: 10.7554/eLife.65068. Elife. 2021. PMID: 34569938 Free PMC article.
A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre.
Molè MA, Coorens THH, Shahbazi MN, Weberling A, Weatherbee BAT, Gantner CW, Sancho-Serra C, Richardson L, Drinkwater A, Syed N, Engley S, Snell P, Christie L, Elder K, Campbell A, Fishel S, Behjati S, Vento-Tormo R, Zernicka-Goetz M. Molè MA, et al. Nat Commun. 2021 Jun 17;12(1):3679. doi: 10.1038/s41467-021-23758-w. Nat Commun. 2021. PMID: 34140473 Free PMC article.
16 results