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Page 1
Genomically humanized mice: technologies and promises.
Devoy A, Bunton-Stasyshyn RK, Tybulewicz VL, Smith AJ, Fisher EM. Devoy A, et al. Nat Rev Genet. 2011 Dec 16;13(1):14-20. doi: 10.1038/nrg3116. Nat Rev Genet. 2011. PMID: 22179716 Free PMC article. Review.
Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome.
Serrano ME, Kim E, Siow B, Ma D, Rojo L, Simmons C, Hayward D, Gibbins D, Singh N, Strydom A, Fisher EMC, Tybulewicz VLJ, Cash D. Serrano ME, et al. Neurobiol Dis. 2023 Nov;188:106336. doi: 10.1016/j.nbd.2023.106336. Neurobiol Dis. 2023. PMID: 38317803 Free PMC article.
Maternal iron deficiency perturbs embryonic cardiovascular development in mice.
Kalisch-Smith JI, Ved N, Szumska D, Munro J, Troup M, Harris SE, Rodriguez-Caro H, Jacquemot A, Miller JJ, Stuart EM, Wolna M, Hardman E, Prin F, Lana-Elola E, Aoidi R, Fisher EMC, Tybulewicz VLJ, Mohun TJ, Lakhal-Littleton S, De Val S, Giannoulatou E, Sparrow DB. Kalisch-Smith JI, et al. Nat Commun. 2021 Jun 8;12(1):3447. doi: 10.1038/s41467-021-23660-5. Nat Commun. 2021. PMID: 34103494 Free PMC article.
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Granno S, Nixon-Abell J, Berwick DC, Tosh J, Heaton G, Almudimeegh S, Nagda Z, Rain JC, Zanda M, Plagnol V, Tybulewicz VLJ, Cleverley K, Wiseman FK, Fisher EMC, Harvey K. Granno S, et al. Sci Rep. 2019 May 13;9(1):7322. doi: 10.1038/s41598-019-43820-4. Sci Rep. 2019. PMID: 31086297 Free PMC article.
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.
Watson-Scales S, Kalmar B, Lana-Elola E, Gibbins D, La Russa F, Wiseman F, Williamson M, Saccon R, Slender A, Olerinyova A, Mahmood R, Nye E, Cater H, Wells S, Yu YE, Bennett DLH, Greensmith L, Fisher EMC, Tybulewicz VLJ. Watson-Scales S, et al. PLoS Genet. 2018 May 10;14(5):e1007383. doi: 10.1371/journal.pgen.1007383. eCollection 2018 May. PLoS Genet. 2018. PMID: 29746474 Free PMC article.
24 results