Brouwer E - Search Results

1

Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo.

Sparreboom A, Verweij J, van der Burg ME, Loos WJ, Brouwer E, Viganò L, Locatelli A, de Vos AI, Nooter K, Stoter G, Gianni L. Sparreboom A, et al. Among authors: brouwer e. Clin Cancer Res. 1998 Aug;4(8):1937-42. Clin Cancer Res. 1998. PMID: 9717822

2

Differential modulation of cisplatin accumulation in leukocytes and tumor cell lines by the paclitaxel vehicle Cremophor EL.

de Vos AI, Nooter K, Verweij J, Loos WJ, Brouwer E, de Bruijn P, Ruijgrok EJ, van der Burg ME, Stoter G, Sparreboom A. de Vos AI, et al. Among authors: brouwer e. Ann Oncol. 1997 Nov;8(11):1145-50. doi: 10.1023/a:1008215720081. Ann Oncol. 1997. PMID: 9426335 Free article.

3

Linearized colorimetric assay for cremophor EL: application to pharmacokinetics after 1-hour paclitaxel infusions.

Brouwer E, Verweij J, Hauns B, Loos WJ, Nooter K, Mross K, Stoter G, Sparreboom A. Brouwer E, et al. Anal Biochem. 1998 Aug 1;261(2):198-202. doi: 10.1006/abio.1998.2746. Anal Biochem. 1998. PMID: 9716422

4

Irinotecan (CPT-11) metabolism and disposition in cancer patients.

Sparreboom A, de Jonge MJ, de Bruijn P, Brouwer E, Nooter K, Loos WJ, van Alphen RJ, Mathijssen RH, Stoter G, Verweij J. Sparreboom A, et al. Among authors: brouwer e. Clin Cancer Res. 1998 Nov;4(11):2747-54. Clin Cancer Res. 1998. PMID: 9829738 Clinical Trial.

5

Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications.

Sparreboom A, van Zuylen L, Brouwer E, Loos WJ, de Bruijn P, Gelderblom H, Pillay M, Nooter K, Stoter G, Verweij J. Sparreboom A, et al. Among authors: brouwer e. Cancer Res. 1999 Apr 1;59(7):1454-7. Cancer Res. 1999. PMID: 10197613

6

Drug-administration sequence does not change pharmacodynamics and kinetics of irinotecan and cisplatin.

de Jonge MJ, Verweij J, Planting AS, van der Burg ME, Stoter G, de Boer-Dennert MM, de Bruijn P, Brouwer E, Vernillet L, Sparreboom A. de Jonge MJ, et al. Among authors: brouwer e. Clin Cancer Res. 1999 Aug;5(8):2012-7. Clin Cancer Res. 1999. PMID: 10473080 Clinical Trial.

7

Disposition of [G-(3)H]paclitaxel and cremophor EL in a patient with severely impaired renal function.

Gelderblom H, Verweij J, Brouwer E, Pillay M, de Bruijn P, Nooter K, Stoter G, Sparreboom A. Gelderblom H, et al. Among authors: brouwer e. Drug Metab Dispos. 1999 Nov;27(11):1300-5. Drug Metab Dispos. 1999. PMID: 10534315

8

Pharmacokinetic, metabolic, and pharmacodynamic profiles in a dose-escalating study of irinotecan and cisplatin.

de Jonge MJ, Verweij J, de Bruijn P, Brouwer E, Mathijssen RH, van Alphen RJ, de Boer-Dennert MM, Vernillet L, Jacques C, Sparreboom A. de Jonge MJ, et al. Among authors: brouwer e. J Clin Oncol. 2000 Jan;18(1):195-203. doi: 10.1200/JCO.2000.18.1.195. J Clin Oncol. 2000. PMID: 10623710

9

Phase I pharmacologic study of oral topotecan and intravenous cisplatin: sequence-dependent hematologic side effects.

de Jonge MJ, Loos WJ, Gelderblom H, Planting AS, van der Burg ME, Sparreboom A, Brouwer E, van Beurden V, Mantel MA, Doyle E, Hearn S, Ross G, Verweij J. de Jonge MJ, et al. Among authors: brouwer e. J Clin Oncol. 2000 May;18(10):2104-15. doi: 10.1200/JCO.2000.18.10.2104. J Clin Oncol. 2000. PMID: 10811676 Clinical Trial.

10

Inter-relationships of paclitaxel disposition, infusion duration and cremophor EL kinetics in cancer patients.

van Zuylen L, Gianni L, Verweij J, Mross K, Brouwer E, Loos WJ, Sparreboom A. van Zuylen L, et al. Among authors: brouwer e. Anticancer Drugs. 2000 Jun;11(5):331-7. doi: 10.1097/00001813-200006000-00003. Anticancer Drugs. 2000. PMID: 10912949 Clinical Trial.

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