Chen IW - Search Results

1

Metabolite-P450 complex formation by methylenedioxyphenyl HIV protease inhibitors in rat and human liver microsomes.

Chiba M, Nishime JA, Chen IW, Vastag KJ, Sahly YS, Kim BM, Dorsey BD, Vacca JP, Lin JH. Chiba M, et al. Among authors: chen iw. Biochem Pharmacol. 1998 Jul 15;56(2):223-30. doi: 10.1016/s0006-2952(98)00139-7. Biochem Pharmacol. 1998. PMID: 9698076

2

Comparison of imidazole- and 2-methyl imidazole-containing farnesyl-protein transferase inhibitors: interaction with and metabolism by rat hepatic cytochrome P450s.

Tang C, Chiba M, Nishime J, Hochman JH, Chen I, Williams TM, Lin JH. Tang C, et al. Drug Metab Dispos. 2000 Jun;28(6):680-6. Drug Metab Dispos. 2000. PMID: 10820141

3

Dose-dependent toxicokinetics of L-689,502, a potent human immunodeficiency virus protease inhibitor, in rats and dogs.

Lin JH, Chen IW, King J. Lin JH, et al. Among authors: chen iw. J Pharmacol Exp Ther. 1992 Oct;263(1):105-11. J Pharmacol Exp Ther. 1992. PMID: 1403775

4

pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs.

Lin JH, Chen IW, Vastag KJ, Ostovic D. Lin JH, et al. Among authors: chen iw. Drug Metab Dispos. 1995 Jul;23(7):730-5. Drug Metab Dispos. 1995. PMID: 7587962

5

Time- and dose-dependent pharmacokinetics of L-754,394, an HIV protease inhibitor, in rats, dogs and monkeys.

Lin JH, Chiba M, Chen IW, Vastag KJ, Nishime JA, Dorsey BD, Michelson SR, McDaniel SL. Lin JH, et al. Among authors: chen iw. J Pharmacol Exp Ther. 1995 Jul;274(1):264-9. J Pharmacol Exp Ther. 1995. PMID: 7616407

6

High-performance liquid chromatographic determination of a potent and selective HIV protease inhibitor (L-735,524) in rat, dog and monkey plasma.

Chen IW, Vastag KJ, Lin JH. Chen IW, et al. J Chromatogr B Biomed Appl. 1995 Oct 6;672(1):111-7. doi: 10.1016/0378-4347(95)00191-k. J Chromatogr B Biomed Appl. 1995. PMID: 8590922

7

Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.

Lin JH, Chiba M, Balani SK, Chen IW, Kwei GY, Vastag KJ, Nishime JA. Lin JH, et al. Among authors: chen iw. Drug Metab Dispos. 1996 Oct;24(10):1111-20. Drug Metab Dispos. 1996. PMID: 8894513

8

Sex-dependent pharmacokinetics of indinavir: in vivo and in vitro evidence.

Lin JH, Chiba M, Chen IW, Nishime JA, Vastag KJ. Lin JH, et al. Among authors: chen iw. Drug Metab Dispos. 1996 Dec;24(12):1298-306. Drug Metab Dispos. 1996. PMID: 8971134

9

Effect of dexamethasone on the intestinal first-pass metabolism of indinavir in rats: evidence of cytochrome P-450 3A [correction of P-450 A] and p-glycoprotein induction.

Lin JH, Chiba M, Chen IW, Nishime JA, deLuna FA, Yamazaki M, Lin YJ. Lin JH, et al. Among authors: chen iw. Drug Metab Dispos. 1999 Oct;27(10):1187-93. Drug Metab Dispos. 1999. PMID: 10497146

10

Route-dependent nonlinear pharmacokinetics of a novel HIV protease inhibitor: involvement of enzyme inactivation.

Lin JH, Chen IW, Chiba M, Nishime JA, Deluna FA. Lin JH, et al. Among authors: chen iw. Drug Metab Dispos. 2000 Apr;28(4):460-6. Drug Metab Dispos. 2000. PMID: 10725315

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