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Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23.
Freimer NB, Reus VI, Escamilla MA, McInnes LA, Spesny M, Leon P, Service SK, Smith LB, Silva S, Rojas E, Gallegos A, Meza L, Fournier E, Baharloo S, Blankenship K, Tyler DJ, Batki S, Vinogradov S, Weissenbach J, Barondes SH, Sandkuijl LA. Freimer NB, et al. Among authors: reus vi. Nat Genet. 1996 Apr;12(4):436-41. doi: 10.1038/ng0496-436. Nat Genet. 1996. PMID: 8630501
A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees.
McInnes LA, Escamilla MA, Service SK, Reus VI, Leon P, Silva S, Rojas E, Spesny M, Baharloo S, Blankenship K, Peterson A, Tyler D, Shimayoshi N, Tobey C, Batki S, Vinogradov S, Meza L, Gallegos A, Fournier E, Smith LB, Barondes SH, Sandkuijl LA, Freimer NB. McInnes LA, et al. Among authors: reus vi. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13060-5. doi: 10.1073/pnas.93.23.13060. Proc Natl Acad Sci U S A. 1996. PMID: 8917544 Free PMC article.
Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18.
Escamilla MA, McInnes LA, Spesny M, Reus VI, Service SK, Shimayoshi N, Tyler DJ, Silva S, Molina J, Gallegos A, Meza L, Cruz ML, Batki S, Vinogradov S, Neylan T, Nguyen JB, Fournier E, Araya C, Barondes SH, Leon P, Sandkuijl LA, Freimer NB. Escamilla MA, et al. Among authors: reus vi. Am J Hum Genet. 1999 Jun;64(6):1670-8. doi: 10.1086/302400. Am J Hum Genet. 1999. PMID: 10330354 Free PMC article.
An association study of bipolar mood disorder (type I) with the 5-HTTLPR serotonin transporter polymorphism in a human population isolate from Colombia.
Ospina-Duque J, Duque C, Carvajal-Carmona L, Ortiz-Barrientos D, Soto I, Pineda N, Cuartas M, Calle J, Lopez C, Ochoa L, Garcia J, Gomez J, Agudelo A, Lozano M, Montoya G, Ospina A, Lopez M, Gallo A, Miranda A, Serna L, Montoya P, Palacio C, Bedoya G, McCarthy M, Reus V, Freimer N, Ruiz-Linares A. Ospina-Duque J, et al. Neurosci Lett. 2000 Oct 13;292(3):199-202. doi: 10.1016/s0304-3940(00)01464-6. Neurosci Lett. 2000. PMID: 11018311
Genome screening for linkage disequilibrium in a Costa Rican sample of patients with bipolar-I disorder: a follow-up study on chromosome 18.
Escamilla MA, McInnes LA, Service SK, Spesny M, Reus VI, Molina J, Gallegos A, Fournier E, Batki S, Neylan T, Matthews C, Vinogradov S, Roche E, Tyler DJ, Shimayoshi N, Mendez R, Ramirez R, Ramirez M, Araya C, Araya X, Leon PE, Sandkuijl LA, Freimer NB. Escamilla MA, et al. Among authors: reus vi. Am J Med Genet. 2001 Mar 8;105(2):207-13. doi: 10.1002/ajmg.1205. Am J Med Genet. 2001. PMID: 11304838
230 results