Tegley CM - Search Results

1

Preparation, resolution, and biological evaluation of 5-aryl-1, 2-dihydro-5H-chromeno[3,4-f]quinolines: potent, orally active, nonsteroidal progesterone receptor agonists.

Edwards JP, Zhi L, Pooley CL, Tegley CM, West SJ, Wang MW, Gottardis MM, Pathirana C, Schrader WT, Jones TK. Edwards JP, et al. Among authors: tegley cm. J Med Chem. 1998 Jul 16;41(15):2779-85. doi: 10.1021/jm980190c. J Med Chem. 1998. PMID: 9667968

2

Synthesis and biological activity of 5-methylidene 1,2-dihydrochromeno[3,4-f]quinoline derivatives as progesterone receptor modulators.

Zhi L, Tegley CM, Pio B, Edwards JP, Jones TK, Marschke KB, Mais DE, Risek B, Schrader WT. Zhi L, et al. Among authors: tegley cm. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2071-4. doi: 10.1016/s0960-894x(03)00255-5. Bioorg Med Chem Lett. 2003. PMID: 12781197

3

Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.

Zhi L, Ringgenberg JD, Edwards JP, Tegley CM, West SJ, Pio B, Motamedi M, Jones TK, Marschke KB, Mais DE, Schrader WT. Zhi L, et al. Among authors: tegley cm. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2075-8. doi: 10.1016/s0960-894x(03)00256-7. Bioorg Med Chem Lett. 2003. PMID: 12781198

4

5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators.

Zhi L, Tegley CM, Pio B, Edwards JP, Motamedi M, Jones TK, Marschke KB, Mais DE, Risek B, Schrader WT. Zhi L, et al. Among authors: tegley cm. J Med Chem. 2003 Sep 11;46(19):4104-12. doi: 10.1021/jm020477g. J Med Chem. 2003. PMID: 12954062

5

Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones.

Higuchi RI, Thompson AW, Chen JH, Caferro TR, Cummings ML, Deckhut CP, Adams ME, Tegley CM, Edwards JP, López FJ, Kallel EA, Karanewsky DS, Schrader WT, Marschke KB, Zhi L. Higuchi RI, et al. Among authors: tegley cm. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5442-6. doi: 10.1016/j.bmcl.2007.07.034. Epub 2007 Jul 25. Bioorg Med Chem Lett. 2007. PMID: 17703938 Free PMC article.

6

5-Aryl-1,2-dihydrochromeno[3,4-f]quinolines: a novel class of nonsteroidal human progesterone receptor agonists.

Zhi L, Tegley CM, Kallel EA, Marschke KB, Mais DE, Gottardis MM, Jones TK. Zhi L, et al. Among authors: tegley cm. J Med Chem. 1998 Jan 29;41(3):291-302. doi: 10.1021/jm9705768. J Med Chem. 1998. PMID: 9464360

7

5-Benzylidene 1,2-dihydrochromeno[3,4-f]quinolines, a novel class of nonsteroidal human progesterone receptor agonists.

Tegley CM, Zhi L, Marschke KB, Gottardis MM, Yang Q, Jones TK. Tegley CM, et al. J Med Chem. 1998 Oct 22;41(22):4354-9. doi: 10.1021/jm980366a. J Med Chem. 1998. PMID: 9784110

8

Nonsteroidal progesterone receptor antagonists based on a conformationally-restricted subseries of 6-aryl-1,2-dihydro-2,2,4-trimethylquinolines.

Hamann LG, Winn DT, Pooley CL, Tegley CM, West SJ, Farmer LJ, Zhi L, Edwards JP, Marschke KB, Mais DE, Goldman ME, Jones TK. Hamann LG, et al. Among authors: tegley cm. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2731-6. doi: 10.1016/s0960-894x(98)00482-x. Bioorg Med Chem Lett. 1998. PMID: 9873612

9

5-Alkyl 1,2-dihydrochromeno[3,4-f]quinolines: a novel class of nonsteroidal progesterone receptor modulators.

Zhi L, Tegley CM, Edwards JP, West SJ, Marschke KB, Gottardis MM, Mais DE, Jones TK. Zhi L, et al. Among authors: tegley cm. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3365-70. doi: 10.1016/s0960-894x(98)00608-8. Bioorg Med Chem Lett. 1998. PMID: 9873735

10

5-Aryl-1,2,3,4-tetrahydrochromeno[3,4-f]quinolin-3-ones as a novel class of nonsteroidal progesterone receptor agonists: effect of A-ring modification.

Zhi L, Tegley CM, Marschke KB, Mais DE, Jones TK. Zhi L, et al. Among authors: tegley cm. J Med Chem. 1999 Apr 22;42(8):1466-72. doi: 10.1021/jm980723h. J Med Chem. 1999. PMID: 10212133

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