Caravatti G - Search Results

1

Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands.

Rahuel J, García-Echeverría C, Furet P, Strauss A, Caravatti G, Fretz H, Schoepfer J, Gay B. Rahuel J, et al. Among authors: caravatti g. J Mol Biol. 1998 Jun 19;279(4):1013-22. doi: 10.1006/jmbi.1998.1790. J Mol Biol. 1998. PMID: 9642078

2

Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.

Gay B, Furet P, García-Echeverría C, Rahuel J, Chène P, Fretz H, Schoepfer J, Caravatti G. Gay B, et al. Among authors: caravatti g. Biochemistry. 1997 May 13;36(19):5712-8. doi: 10.1021/bi962642y. Biochemistry. 1997. PMID: 9153411

3

Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain.

Furet P, Gay B, García-Echeverría C, Rahuel J, Fretz H, Schoepfer J, Caravatti G. Furet P, et al. Among authors: caravatti g. J Med Chem. 1997 Oct 24;40(22):3551-6. doi: 10.1021/jm9702185. J Med Chem. 1997. PMID: 9357522

4

Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2.

García-Echeverría C, Furet P, Gay B, Fretz H, Rahuel J, Schoepfer J, Caravatti G. García-Echeverría C, et al. Among authors: caravatti g. J Med Chem. 1998 May 21;41(11):1741-4. doi: 10.1021/jm970856n. J Med Chem. 1998. PMID: 9599224 No abstract available.

5

Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain.

Furet P, Gay B, Caravatti G, García-Echeverría C, Rahuel J, Schoepfer J, Fretz H. Furet P, et al. Among authors: caravatti g. J Med Chem. 1998 Aug 27;41(18):3442-9. doi: 10.1021/jm980159a. J Med Chem. 1998. PMID: 9719597

6

Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain.

Schoepfer J, Gay B, Caravatti G, Garcia-Echeverria C, Fretz H, Rahuel J, Furet P. Schoepfer J, et al. Among authors: caravatti g. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2865-70. doi: 10.1016/s0960-894x(98)00513-7. Bioorg Med Chem Lett. 1998. PMID: 9873638

7

Highly potent inhibitors of the Grb2-SH2 domain.

Schoepfer J, Fretz H, Gay B, Furet P, García-Echeverría C, End N, Caravatti G. Schoepfer J, et al. Among authors: caravatti g. Bioorg Med Chem Lett. 1999 Jan 18;9(2):221-6. doi: 10.1016/s0960-894x(98)00701-x. Bioorg Med Chem Lett. 1999. PMID: 10021933

8

Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility.

Gay B, Suarez S, Weber C, Rahuel J, Fabbro D, Furet P, Caravatti G, Schoepfer J. Gay B, et al. Among authors: caravatti g. J Biol Chem. 1999 Aug 13;274(33):23311-5. doi: 10.1074/jbc.274.33.23311. J Biol Chem. 1999. PMID: 10438507 Free article.

9

Structure-based design of a non-peptidic antagonist of the SH2 domain of GRB2.

Caravatti G, Rahuel J, Gay B, Furet P. Caravatti G, et al. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1973-8. doi: 10.1016/s0960-894x(99)00299-1. Bioorg Med Chem Lett. 1999. PMID: 10450965

10

Selective GRB2 SH2 inhibitors as anti-Ras therapy.

Gay B, Suarez S, Caravatti G, Furet P, Meyer T, Schoepfer J. Gay B, et al. Among authors: caravatti g. Int J Cancer. 1999 Oct 8;83(2):235-41. doi: 10.1002/(sici)1097-0215(19991008)83:2<235::aid-ijc15>3.0.co;2-b. Int J Cancer. 1999. PMID: 10471533

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