Nakai H - Search Results

1

Adeno-associated viral vector-mediated gene transfer of human blood coagulation factor IX into mouse liver.

Nakai H, Herzog RW, Hagstrom JN, Walter J, Kung SH, Yang EY, Tai SJ, Iwaki Y, Kurtzman GJ, Fisher KJ, Colosi P, Couto LB, High KA. Nakai H, et al. Blood. 1998 Jun 15;91(12):4600-7. Blood. 1998. PMID: 9616156 Free article.

2

Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy.

Grimm D, Zhou S, Nakai H, Thomas CE, Storm TA, Fuess S, Matsushita T, Allen J, Surosky R, Lochrie M, Meuse L, McClelland A, Colosi P, Kay MA. Grimm D, et al. Among authors: nakai h. Blood. 2003 Oct 1;102(7):2412-9. doi: 10.1182/blood-2003-02-0495. Epub 2003 Jun 5. Blood. 2003. PMID: 12791653 Free article.

3

Isolation of recombinant adeno-associated virus vector-cellular DNA junctions from mouse liver.

Nakai H, Iwaki Y, Kay MA, Couto LB. Nakai H, et al. J Virol. 1999 Jul;73(7):5438-47. doi: 10.1128/JVI.73.7.5438-5447.1999. J Virol. 1999. PMID: 10364291 Free PMC article.

4

Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein.

Burton M, Nakai H, Colosi P, Cunningham J, Mitchell R, Couto L. Burton M, et al. Among authors: nakai h. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12725-30. doi: 10.1073/pnas.96.22.12725. Proc Natl Acad Sci U S A. 1999. PMID: 10535990 Free PMC article.

5

Modified infusion procedures affect recombinant adeno-associated virus vector type 2 transduction in the liver.

Ohashi K, Nakai H, Couto LB, Kay MA. Ohashi K, et al. Among authors: nakai h. Hum Gene Ther. 2005 Mar;16(3):299-306. doi: 10.1089/hum.2005.16.299. Hum Gene Ther. 2005. PMID: 15812225

6

Gene delivery to human chondrocytes by an adeno associated virus vector.

Arai Y, Kubo T, Fushiki S, Mazda O, Nakai H, Iwaki Y, Imanishi J, Hirasawa Y. Arai Y, et al. Among authors: nakai h. J Rheumatol. 2000 Apr;27(4):979-82. J Rheumatol. 2000. PMID: 10782826

7

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.

Manno CS, Pierce GF, Arruda VR, Glader B, Ragni M, Rasko JJ, Ozelo MC, Hoots K, Blatt P, Konkle B, Dake M, Kaye R, Razavi M, Zajko A, Zehnder J, Rustagi PK, Nakai H, Chew A, Leonard D, Wright JF, Lessard RR, Sommer JM, Tigges M, Sabatino D, Luk A, Jiang H, Mingozzi F, Couto L, Ertl HC, High KA, Kay MA. Manno CS, et al. Among authors: nakai h. Nat Med. 2006 Mar;12(3):342-7. doi: 10.1038/nm1358. Epub 2006 Feb 12. Nat Med. 2006. PMID: 16474400 Clinical Trial.

8

Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype.

Grimm D, Pandey K, Nakai H, Storm TA, Kay MA. Grimm D, et al. Among authors: nakai h. J Virol. 2006 Jan;80(1):426-39. doi: 10.1128/JVI.80.1.426-439.2006. J Virol. 2006. PMID: 16352567 Free PMC article.

9

A limited number of transducible hepatocytes restricts a wide-range linear vector dose response in recombinant adeno-associated virus-mediated liver transduction.

Nakai H, Thomas CE, Storm TA, Fuess S, Powell S, Wright JF, Kay MA. Nakai H, et al. J Virol. 2002 Nov;76(22):11343-9. doi: 10.1128/jvi.76.22.11343-11349.2002. J Virol. 2002. PMID: 12388694 Free PMC article.

10

Pathways of removal of free DNA vector ends in normal and DNA-PKcs-deficient SCID mouse hepatocytes transduced with rAAV vectors.

Nakai H, Storm TA, Fuess S, Kay MA. Nakai H, et al. Hum Gene Ther. 2003 Jun 10;14(9):871-81. doi: 10.1089/104303403765701169. Hum Gene Ther. 2003. PMID: 12828858

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