Torbett BE - Search Results

1

Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo.

Lee T, Laco GS, Torbett BE, Fox HS, Lerner DL, Elder JH, Wong CH. Lee T, et al. Among authors: torbett be. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):939-44. doi: 10.1073/pnas.95.3.939. Proc Natl Acad Sci U S A. 1998. PMID: 9448264 Free PMC article.

2

Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion.

Steinberger P, Andris-Widhopf J, Bühler B, Torbett BE, Barbas CF 3rd. Steinberger P, et al. Among authors: torbett be. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):805-10. doi: 10.1073/pnas.97.2.805. Proc Natl Acad Sci U S A. 2000. PMID: 10639161 Free PMC article.

3

Viral evolution in response to the broad-based retroviral protease inhibitor TL-3.

Bühler B, Lin YC, Morris G, Olson AJ, Wong CH, Richman DD, Elder JH, Torbett BE. Bühler B, et al. Among authors: torbett be. J Virol. 2001 Oct;75(19):9502-8. doi: 10.1128/JVI.75.19.9502-9508.2001. J Virol. 2001. PMID: 11533212 Free PMC article.

4

Is resistance futile?

Kutilek VD, Sheeter DA, Elder JH, Torbett BE. Kutilek VD, et al. Among authors: torbett be. Curr Drug Targets Infect Disord. 2003 Dec;3(4):295-309. doi: 10.2174/1568005033481079. Curr Drug Targets Infect Disord. 2003. PMID: 14754431 Review.

5

Resolution and prevention of feline immunodeficiency virus-induced neurological deficits by treatment with the protease inhibitor TL-3.

Huitron-Resendiz S, De Rozières S, Sanchez-Alavez M, Bühler B, Lin YC, Lerner DL, Henriksen NW, Burudi M, Fox HS, Torbett BE, Henriksen S, Elder JH. Huitron-Resendiz S, et al. Among authors: torbett be. J Virol. 2004 May;78(9):4525-32. doi: 10.1128/jvi.78.9.4525-4532.2004. J Virol. 2004. PMID: 15078933 Free PMC article.

6

Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3.

de Rozières S, Swan CH, Sheeter DA, Clingerman KJ, Lin YC, Huitron-Resendiz S, Henriksen S, Torbett BE, Elder JH. de Rozières S, et al. Among authors: torbett be. Retrovirology. 2004 Nov 19;1:38. doi: 10.1186/1742-4690-1-38. Retrovirology. 2004. PMID: 15555065 Free PMC article.

7

Structural insights into the mechanisms of drug resistance in HIV-1 protease NL4-3.

Heaslet H, Kutilek V, Morris GM, Lin YC, Elder JH, Torbett BE, Stout CD. Heaslet H, et al. Among authors: torbett be. J Mol Biol. 2006 Mar 3;356(4):967-81. doi: 10.1016/j.jmb.2005.11.094. Epub 2005 Dec 20. J Mol Biol. 2006. PMID: 16403521

8

Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system.

Lin YC, Brik A, de Parseval A, Tam K, Torbett BE, Wong CH, Elder JH. Lin YC, et al. Among authors: torbett be. J Virol. 2006 Aug;80(16):7832-43. doi: 10.1128/JVI.00374-06. J Virol. 2006. PMID: 16873240 Free PMC article.

9

Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3.

Heaslet H, Lin YC, Tam K, Torbett BE, Elder JH, Stout CD. Heaslet H, et al. Among authors: torbett be. Retrovirology. 2007 Jan 9;4:1. doi: 10.1186/1742-4690-4-1. Retrovirology. 2007. PMID: 17212810 Free PMC article.

10

Conformational flexibility in the flap domains of ligand-free HIV protease.

Heaslet H, Rosenfeld R, Giffin M, Lin YC, Tam K, Torbett BE, Elder JH, McRee DE, Stout CD. Heaslet H, et al. Among authors: torbett be. Acta Crystallogr D Biol Crystallogr. 2007 Aug;63(Pt 8):866-75. doi: 10.1107/S0907444907029125. Epub 2007 Jul 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17642513

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