Heitman J - Search Results

1

All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae.

Dolinski K, Muir S, Cardenas M, Heitman J. Dolinski K, et al. Among authors: heitman j. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13093-8. doi: 10.1073/pnas.94.24.13093. Proc Natl Acad Sci U S A. 1997. PMID: 9371805 Free PMC article.

2

A yeast cyclophilin gene essential for lactate metabolism at high temperature.

Davis ES, Becker A, Heitman J, Hall MN, Brennan MB. Davis ES, et al. Among authors: heitman j. Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11169-73. doi: 10.1073/pnas.89.23.11169. Proc Natl Acad Sci U S A. 1992. PMID: 1454795 Free PMC article.

3

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae.

Heitman J, Movva NR, Hiestand PC, Hall MN. Heitman J, et al. Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1948-52. doi: 10.1073/pnas.88.5.1948. Proc Natl Acad Sci U S A. 1991. PMID: 1705713 Free PMC article.

4

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.

Lorenz MC, Heitman J. Lorenz MC, et al. Among authors: heitman j. J Biol Chem. 1995 Nov 17;270(46):27531-7. doi: 10.1074/jbc.270.46.27531. J Biol Chem. 1995. PMID: 7499212 Free article.

5

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

Breuder T, Hemenway CS, Movva NR, Cardenas ME, Heitman J. Breuder T, et al. Among authors: heitman j. Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5372-6. doi: 10.1073/pnas.91.12.5372. Proc Natl Acad Sci U S A. 1994. PMID: 7515500 Free PMC article.

6

Antifungal effects of cyclosporine and FK 506 are mediated via immunophilin-dependent calcineurin inhibition.

Heitman J, Cardenas ME, Breuder T, Hemenway C, Muir RS, Lim E, Goetz L, Zhu D, Lorenz M, Dolinski K. Heitman J, et al. Transplant Proc. 1994 Oct;26(5):2833-4. Transplant Proc. 1994. PMID: 7524220 No abstract available.

7

Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.

Cardenas ME, Hemenway C, Muir RS, Ye R, Fiorentino D, Heitman J. Cardenas ME, et al. Among authors: heitman j. EMBO J. 1994 Dec 15;13(24):5944-57. doi: 10.1002/j.1460-2075.1994.tb06940.x. EMBO J. 1994. PMID: 7529175 Free PMC article.

8

Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.

Cardenas ME, Muir RS, Breuder T, Heitman J. Cardenas ME, et al. Among authors: heitman j. EMBO J. 1995 Jun 15;14(12):2772-83. doi: 10.1002/j.1460-2075.1995.tb07277.x. EMBO J. 1995. PMID: 7540976 Free PMC article.

9

Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae.

Zhu D, Cardenas ME, Heitman J. Zhu D, et al. Among authors: heitman j. J Biol Chem. 1995 Oct 20;270(42):24831-8. doi: 10.1074/jbc.270.42.24831. J Biol Chem. 1995. PMID: 7559604 Free article.

10

Mutations that perturb cyclophilin A ligand binding pocket confer cyclosporin A resistance in Saccharomyces cerevisiae.

Cardenas ME, Lim E, Heitman J. Cardenas ME, et al. Among authors: heitman j. J Biol Chem. 1995 Sep 8;270(36):20997-1002. doi: 10.1074/jbc.270.36.20997. J Biol Chem. 1995. PMID: 7673124 Free article.

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