Seibel WL - Search Results

1

Highly sensitive high-performance liquid chromatographic-tandem mass spectrometric method for the analysis of dextromethorphan in human plasma.

Eichhold TH, Quijano M, Seibel WL, Cruze CA, Dobson RL, Wehmeyer KR. Eichhold TH, et al. Among authors: seibel wl. J Chromatogr B Biomed Sci Appl. 1997 Sep 26;698(1-2):147-54. doi: 10.1016/s0378-4347(97)00308-3. J Chromatogr B Biomed Sci Appl. 1997. PMID: 9367202

2

Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens.

Hu XE, Kim NK, Gray JL, Almstead JI, Seibel WL, Ledoussal B. Hu XE, et al. Among authors: seibel wl. J Med Chem. 2003 Aug 14;46(17):3655-61. doi: 10.1021/jm030272n. J Med Chem. 2003. PMID: 12904069

3

Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.

Evdokimov AG, Pokross M, Walter RL, Mekel M, Barnett BL, Amburgey J, Seibel WL, Soper SJ, Djung JF, Fairweather N, Diven C, Rastogi V, Grinius L, Klanke C, Siehnel R, Twinem T, Andrews R, Curnow A. Evdokimov AG, et al. Among authors: seibel wl. Proteins. 2007 Feb 15;66(3):538-46. doi: 10.1002/prot.21207. Proteins. 2007. PMID: 17120228

4

Theoretical and practical considerations in virtual screening: a beaten field?

Kontoyianni M, Madhav P, Suchanek E, Seibel W. Kontoyianni M, et al. Curr Med Chem. 2008;15(2):107-16. doi: 10.2174/092986708783330566. Curr Med Chem. 2008. PMID: 18220766 Review.

5

Multiplex enzyme assays and inhibitor screening by mass spectrometry.

Rathore R, Pribil P, Corr JJ, Seibel WL, Evdokimov A, Greis KD. Rathore R, et al. Among authors: seibel wl. J Biomol Screen. 2010 Sep;15(8):1001-7. doi: 10.1177/1087057110363824. Epub 2010 Mar 12. J Biomol Screen. 2010. PMID: 20228278

6

Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates.

Rathore R, Corr JJ, Lebre DT, Seibel WL, Greis KD. Rathore R, et al. Among authors: seibel wl. Rapid Commun Mass Spectrom. 2009 Oct 30;23(20):3293-300. doi: 10.1002/rcm.4248. Rapid Commun Mass Spectrom. 2009. PMID: 19757451

7

Expansion of first-in-class drug candidates that sequester toxic all-trans-retinal and prevent light-induced retinal degeneration.

Zhang J, Dong Z, Mundla SR, Hu XE, Seibel W, Papoian R, Palczewski K, Golczak M. Zhang J, et al. Mol Pharmacol. 2015;87(3):477-91. doi: 10.1124/mol.114.096560. Epub 2014 Dec 23. Mol Pharmacol. 2015. PMID: 25538117 Free PMC article.

8

Discovery of a novel class of potent HCV NS4B inhibitors: SAR studies on piperazinone derivatives.

Kakarla R, Liu J, Naduthambi D, Chang W, Mosley RT, Bao D, Steuer HM, Keilman M, Bansal S, Lam AM, Seibel W, Neilson S, Furman PA, Sofia MJ. Kakarla R, et al. J Med Chem. 2014 Mar 13;57(5):2136-60. doi: 10.1021/jm4012643. Epub 2014 Jan 29. J Med Chem. 2014. PMID: 24476391

9

High-throughput screening for small-molecule inhibitors of Staphylococcus epidermidis RP62a biofilms.

Panmanee W, Taylor D, Shea CJ, Tang H, Nelson S, Seibel W, Papoian R, Kramer R, Hassett DJ, Lamkin TJ. Panmanee W, et al. J Biomol Screen. 2013 Aug;18(7):820-9. doi: 10.1177/1087057113481499. Epub 2013 Mar 29. J Biomol Screen. 2013. PMID: 23543429

10

Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia.

Barreyro L, Sampson AM, Ishikawa C, Hueneman KM, Choi K, Pujato MA, Chutipongtanate S, Wyder M, Haffey WD, O'Brien E, Wunderlich M, Ramesh V, Kolb EM, Meydan C, Neelamraju Y, Bolanos LC, Christie S, Smith MA, Niederkorn M, Muto T, Kesari S, Garrett-Bakelman FE, Bartholdy B, Will B, Weirauch MT, Mulloy JC, Gul Z, Medlin S, Kovall RA, Melnick AM, Perentesis JP, Greis KD, Nurmemmedov E, Seibel WL, Starczynowski DT. Barreyro L, et al. Among authors: seibel wl. Sci Transl Med. 2022 Mar 9;14(635):eabb7695. doi: 10.1126/scitranslmed.abb7695. Epub 2022 Mar 9. Sci Transl Med. 2022. PMID: 35263148

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